| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Larry Baum, Chi Chiu Lee, Rui Ye, Yuanxin Zhong, Se Fong Hung, Chun Pan Tang, Ting Pong Ho, James M Swanson, Robert K Moyzis, Pak-Chung Sham, Patrick Wing-Leung Leun. Attention-deficit/hyperactivity disorder and dopamine receptor D4 (DRD4) exon 3 variable number of tandem repeats (VNTR) 2-repeat allele. Annals of human genetics. 2024-04-16. PMID:38624263. |
to investigate the association of attention-deficit/hyperactivity disorder (adhd) with the 48-base pair (bp) variable number of tandem repeats (vntr) in exon 3 of the dopamine receptor d4 (drd4) gene, we genotyped 240 adhd patients and their parents from hong kong. |
2024-04-16 |
2024-04-18 |
Not clear |
| Johanna Inhyang Kim, Jae-Won Kim, Inkyung Shin, Bung-Nyun Ki. Effects of Interaction Between DRD4 Methylation and Prenatal Maternal Stress on Methylphenidate-Induced Changes in Continuous Performance Test Performance in Youth with Attention-Deficit/Hyperactivity Disorder. Journal of child and adolescent psychopharmacology. vol 28. issue 8. 2019-10-04. PMID:29905488. |
the purpose of this study was to investigate the interaction effects between dopamine receptor d4 (drd4) methylation and prenatal maternal stress on the methylphenidate (mph) response of youth with attention-deficit/hyperactivity disorder (adhd). |
2019-10-04 |
2023-08-13 |
Not clear |
| Dennis van der Meer, Catharina A Hartman, Daan van Rooij, Barbara Franke, Dirk J Heslenfeld, Jaap Oosterlaan, Stephen V Faraone, Jan K Buitelaar, Pieter J Hoekstr. Effects of dopaminergic genes, prenatal adversities, and their interaction on attention-deficit/hyperactivity disorder and neural correlates of response inhibition. Journal of psychiatry & neuroscience : JPN. vol 42. issue 2. 2018-01-08. PMID:28234207. |
given that prenatal exposure to alcohol or smoking is known to affect dopamine-rich brain regions, we hypothesized that individuals carrying the adhd risk alleles of the dopamine receptor d4 ( |
2018-01-08 |
2023-08-13 |
Not clear |
| Subin Park, Bung-Nyun Kim, Jae-Won Kim, Min-Sup Shin, Hee Jeong Yoo, Soo-Churl Ch. Interactions Between Early Trauma and Catechol-O-Methyltransferase Genes on Inhibitory Deficits in Children With ADHD. Journal of attention disorders. vol 21. issue 3. 2017-12-04. PMID:25063767. |
to investigate the interaction between childhood trauma exposure with the catechol-o-methyltransferase (comt) and dopamine receptor d4 (drd4) polymorphisms in relation to neuropsychological measures in children with adhd. |
2017-12-04 |
2023-08-13 |
Not clear |
| Patrick Wing-Leung Leung, Janice Ka Yan Chan, Lu Hua Chen, Chi Chiu Lee, Se Fong Hung, Ting Pong Ho, Chun Pan Tang, Robert K Moyzis, James M Swanso. Family-based association study of DRD4 gene in methylphenidate-responded Attention Deficit/Hyperactivity Disorder. PloS one. vol 12. issue 3. 2017-08-17. PMID:28282463. |
the 48-basepair (48-bp) variable number tandem repeat (vntr) polymorphism in exon 3 of the dopamine receptor d4 gene (drd4) is implicated in the etiology of attention-deficit/ hyperactivity disorder (adhd). |
2017-08-17 |
2023-08-13 |
Not clear |
| Björn Albrecht, Daniel Brandeis, Henrik Uebel-von Sandersleben, Lilian Valko, Hartmut Heinrich, Xiaohui Xu, Renate Drechsler, Alexander Heise, Jonna Kuntsi, Ueli C Müller, Philip Asherson, Hans-Christoph Steinhausen, Aribert Rothenberger, Tobias Banaschewsk. Genetics of preparation and response control in ADHD: the role of DRD4 and DAT1. Journal of child psychology and psychiatry, and allied disciplines. vol 55. issue 8. 2015-06-22. PMID:24521003. |
the aim of this study was to clarify the impact of dopamine receptor d4 (drd4) and dopamine transporter (dat1) gene polymorphisms on these processes in adhd and control children. |
2015-06-22 |
2023-08-12 |
Not clear |
| Salvador Trejo, José J Toscano-Flores, Esmeralda Matute, María de Lourdes Ramírez-Dueña. Hardy-Weinberg equilibrium analysis of the 48 bp VNTR in the III exon of the DRD4 gene in a sample of parents of ADHD cases. The application of clinical genetics. vol 8. 2015-06-17. PMID:26082657. |
the aim of this study was to obtain the genotype and gene frequency from parents of children with attention-deficit/hyperactivity disorder (adhd) and then assess the hardy-weinberg equilibrium of genotype frequency of the variable number tandem repeat (vntr) iii exon of the dopamine receptor d4 (drd4) gene. |
2015-06-17 |
2023-08-13 |
Not clear |
| Subin Park, Bung-Nyun Kim, Soo-Churl Cho, Yeni Kim, Jae-Won Kim, Ju-Young Lee, Soon-Beom Hong, Min-Sup Shin, Hee Jeong Yoo, Hosub Im, Jae Hoon Cheong, Doug Hyun Ha. Association between urine phthalate levels and poor attentional performance in children with attention-deficit hyperactivity disorder with evidence of dopamine gene-phthalate interaction. International journal of environmental research and public health. vol 11. issue 7. 2015-02-25. PMID:24978879. |
correlations between urine phthalate metabolite concentrations and the cpt scores were investigated, and the interaction of phthalate metabolite levels with the selected polymorphisms at major candidate genes for adhd, namely dopamine receptor d4 (drd4), dopamine transporter, α-2a-adrenergic receptor, and norepinephrine transporter genes. |
2015-02-25 |
2023-08-13 |
human |
| Gina Marie Mason, Goffredina Spanó, Jamie Edgi. Symptoms of attention-deficit/hyperactivity disorder in Down syndrome: effects of the dopamine receptor D4 gene. American journal on intellectual and developmental disabilities. vol 120. issue 1. 2015-02-11. PMID:25551267. |
this study examined individual differences in adhd symptoms and executive function (ef) in children with down syndrome (ds) in relation to the dopamine receptor d4 (drd4) gene, a gene often linked to adhd in people without ds. |
2015-02-11 |
2023-08-13 |
human |
| Luciana Tovo-Rodrigues, Luis A Rohde, Ana M B Menezes, Guilherme V Polanczyk, Christian Kieling, Julia P Genro, Luciana Anselmi, Mara H Hut. DRD4 rare variants in Attention-Deficit/Hyperactivity Disorder (ADHD): further evidence from a birth cohort study. PloS one. vol 8. issue 12. 2014-09-02. PMID:24391992. |
the dopamine receptor d4 (drd4) is one of the most studied candidate genes for attention-deficit/hyperactivity disorder (adhd). |
2014-09-02 |
2023-08-12 |
human |
| Allison Maxwel. Are some individuals diagnosed with ADHD prone to alcohol abuse? Consideration of two possible mediating factors for this susceptibility. Journal of attention disorders. vol 17. issue 2. 2013-06-28. PMID:22100688. |
it is proposed that those individuals diagnosed with adhd who also have a mutation in the dopamine receptor d4 (drd4) and who possess a deficiency in functionality of the prefrontal area of the brain designed for planning and reasoning may be more likely to develop alcohol abuse. |
2013-06-28 |
2023-08-12 |
Not clear |
| Hyun Soo Ji, Ki Chung Paik, Woo Sung Park, Myung Ho Li. No Association between the Response to Methylphenidate and DRD4 Gene Polymorphism in Korean Attention Deficit Hyperactivity Disorder: A Case Control Study. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 11. issue 1. 2013-05-17. PMID:23678349. |
we investigated the association between the genetic type, alleles and drug response for the dopamine receptor d4 (drd4) gene in adhd patients in korea. |
2013-05-17 |
2023-08-12 |
Not clear |
| Marieke E Altink, Nanda N J Rommelse, Dorine I E Slaats-Willemse, Alejandro Arias Vásquez, Barbara Franke, Cathelijne J M Buschgens, Ellen A Fliers, Stephen V Faraone, Joseph A Sergeant, Jaap Oosterlaan, Jan K Buitelaa. The dopamine receptor D4 7-repeat allele influences neurocognitive functioning, but this effect is moderated by age and ADHD status: an exploratory study. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 13. issue 4. 2012-09-17. PMID:22111665. |
the dopamine receptor d4 7-repeat allele influences neurocognitive functioning, but this effect is moderated by age and adhd status: an exploratory study. |
2012-09-17 |
2023-08-12 |
Not clear |
| L Tovo-Rodrigues, L A Rohde, T Roman, M Schmitz, G Polanczyk, C Zeni, F Z C Marques, V Contini, E H Grevet, P Belmonte-de-Abreu, C H D Bau, M H Hut. Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD? Searching for an effect of allelic heterogeneity. Molecular psychiatry. vol 17. issue 5. 2012-08-29. PMID:21403674. |
although several studies have demonstrated an association between the 7-repeat (7r) allele in the 48-bp variable number of tandem repeats (vntrs) in the exon 3 at dopamine receptor d4 (drd4) gene and attention-deficit/hyperactivity disorder (adhd), others failed to replicate this finding. |
2012-08-29 |
2023-08-12 |
human |
| Zeynep Yilmaz, Allan S Kaplan, Robert D Levitan, Clement C Zai, James L Kenned. Possible association of the DRD4 gene with a history of attention-deficit/hyperactivity disorder in women with bulimia nervosa. The International journal of eating disorders. vol 45. issue 4. 2012-08-10. PMID:22271608. |
up to one-third of patients with bulimia nervosa (bn) report a history of attention-deficit/hyperactivity disorder (adhd) symptoms, and the dopaminergic genes, especially the dopamine receptor d4 (drd4), have been associated independently with both binge eating and adhd. |
2012-08-10 |
2023-08-12 |
Not clear |
| Michelle M Martel, Molly Nikolas, Katherine Jernigan, Karen Friderici, Irwin Waldman, Joel T Nig. The dopamine receptor D4 gene (DRD4) moderates family environmental effects on ADHD. Journal of abnormal child psychology. vol 39. issue 1. 2011-06-01. PMID:20644990. |
the dopamine receptor d4 gene (drd4) moderates family environmental effects on adhd. |
2011-06-01 |
2023-08-12 |
human |
| Judith G Auerbach, Naama Atzaba-Poria, Andrea Berger, Rivka Landau, Shoshana Arbelle, Yael Raz, Richard Ebstei. Dopamine risk and paternal ADHD symptomatology associated with ADHD symptoms in four and a half-year-old boys. Psychiatric genetics. vol 20. issue 4. 2010-11-04. PMID:20421851. |
this study examined the influence of allelic variation in two dopamine genes, the dopamine receptor d4 (drd4) gene and the dopamine transporter d1 (dat1) gene, and paternal attention-deficit hyperactivity disorder (adhd) symptomatology on the level of adhd symptoms in 96 four and a half-year-old boys. |
2010-11-04 |
2023-08-12 |
Not clear |
| Sandra K Loo, Sigi T Hale, Grant Hanada, James Macion, Anshu Shrestha, James J McGough, James T McCracken, Stanley Nelson, Susan L Smalle. Familial clustering and DRD4 effects on electroencephalogram measures in multiplex families with attention deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry. vol 49. issue 4. 2010-08-02. PMID:20410729. |
the current study tests electroencephalogram (eeg) measures as a potential endophenotype for attention deficit/hyperactivity disorder (adhd) by examining sibling and parent-offspring similarity, familial clustering with the disorder, and association with the dopamine receptor d4 (drd4) candidate gene. |
2010-08-02 |
2023-08-12 |
Not clear |
| Katja Becker, Dorothea Blomeyer, Mahha El-Faddagh, Guenter Esser, Martin H Schmidt, Tobias Banaschewski, Manfred Lauch. From regulatory problems in infancy to attention-deficit/hyperactivity disorder in childhood: a moderating role for the dopamine D4 receptor gene? The Journal of pediatrics. vol 156. issue 5. 2010-05-03. PMID:20172533. |
to examine whether the dopamine receptor d4 gene (drd4) exon iii vntr moderates the risk of infants with regulatory disorders for developing attention-deficit/hyperactivity disorder (adhd) later in childhood. |
2010-05-03 |
2023-08-12 |
Not clear |
| Marieke E Altink, Alejandro Arias-Vásquez, Barbara Franke, Dorine I E Slaats-Willemse, Cathelijne J M Buschgens, Nanda N J Rommelse, Ellen A Fliers, Richard Anney, Keeley-Joanne Brookes, Wai Chen, Michael Gill, Aisling Mulligan, Edmund Sonuga-Barke, Margaret Thompson, Joseph A Sergeant, Stephen V Faraone, Philip Asherson, Jan K Buitelaa. The dopamine receptor D4 7-repeat allele and prenatal smoking in ADHD-affected children and their unaffected siblings: no gene-environment interaction. Journal of child psychology and psychiatry, and allied disciplines. vol 49. issue 10. 2009-03-05. PMID:19017022. |
the dopamine receptor d4 (drd4) 7-repeat allele and maternal smoking during pregnancy are both considered as risk factors in the aetiology of attention deficit hyperactivity disorder (adhd), but few studies have been conducted on their interactive effects in causing adhd. |
2009-03-05 |
2023-08-12 |
Not clear |