| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhengyun Han, Xingmao Yang, Shuiqing Huan. Sleep deprivation: A risk factor for the pathogenesis and progression of Alzheimer's disease. Heliyon. vol 10. issue 7. 2024-04-16. PMID:38623196. |
sleep deprivation promotes aβ deposition and tau hyperphosphorylation, which is a risk factor for the pathogenesis and progression of alzheimer's disease (ad). |
2024-04-16 |
2024-04-18 |
Not clear |
| Lina Stålesen Ramfjord, Nikolaj Kahn, Knut Langsrud, Joar Øveraas Øveraas Halvorsen, Gunnar Morken, Simen Saksvik, Liv Sigrun Sættem Engvik, Stian Lydersen, Håvard Kallesta. Chronotherapy for patients with a depressive episode treated in a public outpatient mental healthcare clinic in Norway: protocol for a randomised controlled trial. BMJ open. vol 14. issue 1. 2024-01-03. PMID:38171633. |
chronotherapy, consisting of sleep deprivation, sleep-wake phase advancement and stabilisation, and light therapy, is a possible addition to tau that may decrease the time to treatment response. |
2024-01-03 |
2024-01-06 |
Not clear |
| Per Kristian Eide, Aslan Lashkarivand, Are Hugo Pripp, Lars Magnus Valnes, Markus Hovd, Geir Ringstad, Kaj Blennow, Henrik Zetterber. Mechanisms behind changes of neurodegeneration biomarkers in plasma induced by sleep deprivation. Brain communications. vol 5. issue 6. 2023-12-22. PMID:38130841. |
plasma concentrations of amyloid-β 40 and 42, phosphorylated tau peptide 181, glial fibrillary acid protein and neurofilament light were measured longitudinally in subjects who from day 1 to day 2 either underwent total sleep deprivation ( |
2023-12-22 |
2023-12-24 |
human |
| Hong Cheng, Lu Gan, Yan Wang, Lin Li, Yongle L. Effect of sleep deprivation by MMP-WM on rat neurological function and Tau protein in hippocampus. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 11. 2023-11-28. PMID:38015534. |
effect of sleep deprivation by mmp-wm on rat neurological function and tau protein in hippocampus. |
2023-11-28 |
2023-11-29 |
human |
| Hong Cheng, Lu Gan, Yan Wang, Lin Li, Yongle L. Effect of sleep deprivation by MMP-WM on rat neurological function and Tau protein in hippocampus. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 11. 2023-11-28. PMID:38015534. |
this study aims to explore the effect of sleep deprivation by modified multiple platform-water maze (mmp-wm) on rat neurological function and tau protein in the hippocampus, as well as the intervention effect of remimazolam. |
2023-11-28 |
2023-11-29 |
human |
| Timna Hitrec, Fabio Squarcio, Emiliana Piscitiello, Matteo Cerri, Davide Martelli, Alessandra Occhinegro, Ludovico Taddei, Domenico Tupone, Roberto Amici, Marco Lupp. Sleep deprivation soon after recovery from synthetic torpor enhances tau protein dephosphorylation in the rat brain. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 2023-10-09. PMID:37812305. |
sleep deprivation soon after recovery from synthetic torpor enhances tau protein dephosphorylation in the rat brain. |
2023-10-09 |
2023-10-15 |
rat |
| Aruna Sharma, Lianyuan Feng, Dafin F Muresanu, Z Ryan Tian, José Vicente Lafuente, Anca D Buzoianu, Ala Nozari, Igor Bryukhovetskiy, Igor Manzhulo, Lars Wiklund, Hari Shanker Sharm. Nanowired Delivery of Cerebrolysin Together with Antibodies to Amyloid Beta Peptide, Phosphorylated Tau, and Tumor Necrosis Factor Alpha Induces Superior Neuroprotection in Alzheimer's Disease Brain Pathology Exacerbated by Sleep Deprivation. Advances in neurobiology. vol 32. 2023-07-22. PMID:37480458. |
nanowired delivery of cerebrolysin together with antibodies to amyloid beta peptide, phosphorylated tau, and tumor necrosis factor alpha induces superior neuroprotection in alzheimer's disease brain pathology exacerbated by sleep deprivation. |
2023-07-22 |
2023-08-14 |
Not clear |
| Aruna Sharma, Lianyuan Feng, Dafin F Muresanu, Z Ryan Tian, José Vicente Lafuente, Anca D Buzoianu, Ala Nozari, Igor Bryukhovetskiy, Igor Manzhulo, Lars Wiklund, Hari Shanker Sharm. Nanowired Delivery of Cerebrolysin Together with Antibodies to Amyloid Beta Peptide, Phosphorylated Tau, and Tumor Necrosis Factor Alpha Induces Superior Neuroprotection in Alzheimer's Disease Brain Pathology Exacerbated by Sleep Deprivation. Advances in neurobiology. vol 32. 2023-07-22. PMID:37480458. |
sleep deprivation induces amyloid beta peptide and phosphorylated tau deposits in the brain and cerebrospinal fluid together with altered serotonin metabolism. |
2023-07-22 |
2023-08-14 |
Not clear |
| Katherine R Sadleir, Robert Vassa. Connections between ApoE, sleep, and Aβ and tau pathologies in Alzheimer's disease. The Journal of clinical investigation. vol 133. issue 14. 2023-07-18. PMID:37463448. |
the authors subjected an amyloid mouse model expressing human apoe3 or apoe4, with and without human ad-tau injection, to sleep deprivation and observed that amyloid and tau pathologies were worsened in the presence of apoe4. |
2023-07-18 |
2023-08-14 |
mouse |
| Chanung Wang, Aishwarya Nambiar, Michael R Strickland, Choonghee Lee, Samira Parhizkar, Alec C Moore, Erik S Musiek, Jason D Ulrich, David M Holtzma. APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading. The Journal of clinical investigation. 2023-06-06. PMID:37279069. |
we hypothesized that apoe modifies aβ deposition and aβ plaque-associated tau seeding and spreading in the form of neuritic plaque (np)-tau pathology in response to chronic sleep deprivation (sd) in an apoe isoform-dependent fashion. |
2023-06-06 |
2023-08-14 |
mouse |
| Haiyan Liu, Nicolas R Barthélemy, Vitaliy Ovod, James G Bollinger, Yingxin He, Samir L Chahin, Brendan Androff, Randall J Bateman, Brendan P Luce. Acute sleep loss decreases CSF-to-blood clearance of Alzheimer's disease biomarkers. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-01-25. PMID:36695437. |
sleep deprivation increases cerebrospinal fluid (csf) amyloid beta (aβ) and tau levels; however, sleep's effect on aβ and tau in plasma is unknown. |
2023-01-25 |
2023-08-14 |
Not clear |
| Mengxi Shen, Naqi Lian, Chengcheng Song, Chao Qin, Yang Yu, Yonghao Y. Different Anesthetic Drugs Mediate Changes in Neuroplasticity During Cognitive Impairment in Sleep-Deprived Rats via Different Factors. Medical science monitor : international medical journal of experimental and clinical research. vol 27. 2021-10-05. PMID:34564688. |
sevoflurane anesthesia-induced cognitive impairment following acute sleep deprivation was more pronounced than sleep deprivation-induced cognitive impairment alone and resulted in increased brain sik3 levels, increased phosphorylation of total tau and tau, and decreased acetylation modifications. |
2021-10-05 |
2023-08-13 |
rat |
| Mengxi Shen, Naqi Lian, Chengcheng Song, Chao Qin, Yang Yu, Yonghao Y. Different Anesthetic Drugs Mediate Changes in Neuroplasticity During Cognitive Impairment in Sleep-Deprived Rats via Different Factors. Medical science monitor : international medical journal of experimental and clinical research. vol 27. 2021-10-05. PMID:34564688. |
conclusions these results suggest that sevoflurane inhalation via the sik3 pathway aggravates cognitive impairment after acute sleep deprivation and that propofol anesthesia reverses the effects of sleep deprivation by affecting modifications of tau protein. |
2021-10-05 |
2023-08-13 |
rat |
| Chun Wang, Xu Cao, Jing Yin, Wen-Rui Gao, Wei-Ran Li, Jin-Shun Qi, Mei-Na W. [Chronic sleep deprivation exacerbates cognitive and pathological impairments in APP/PS1/tau triple transgenic Alzheimer's disease model mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 3. 2021-07-08. PMID:34230948. |
the results showed that: (1) chronic sleep deprivation did not affect anxiety- (p = 0.539) and depression-like behaviors (p = 0.874) in 3xtg-ad mice; (2) chronic sleep deprivation exacerbated the impairments of object recognition memory (p < 0.001), working memory (p = 0.002) and the conditioned fear memory (p = 0.039) in 3xtg-ad mice; (3) chronic sleep deprivation increased amyloid β (aβ) deposition (p < 0.001) and microglial activation (p < 0.001) in the hippocampus of 3xtg-ad mice, without inducing abnormal tau phosphorylation and neurofibrillary tangles. |
2021-07-08 |
2023-08-13 |
mouse |
| Chanung Wang, David M Holtzma. Bidirectional relationship between sleep and Alzheimer's disease: role of amyloid, tau, and other factors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 1. 2020-12-16. PMID:31408876. |
new findings from our group reveal that acute sleep deprivation increases levels of tau in mouse brain interstitial fluid (isf) and human cerebrospinal fluid (csf) and chronic sleep deprivation accelerates the spread of tau protein aggregates in neural networks. |
2020-12-16 |
2023-08-13 |
mouse |
| Md Sahab Uddin, Devesh Tewari, Abdullah Al Mamun, Md Tanvir Kabir, Kamal Niaz, Mir Imam Ibne Wahed, George E Barreto, Ghulam Md Ashra. Circadian and sleep dysfunction in Alzheimer's disease. Ageing research reviews. vol 60. 2020-11-03. PMID:32171783. |
besides aβ, the impact of tau pathology is possibly noteworthy to the sleep deprivation found in ad. |
2020-11-03 |
2023-08-13 |
Not clear |
| Nahid Ahmadian, Sajjad Hejazi, Javad Mahmoudi, Mahnaz Taleb. Tau Pathology of Alzheimer Disease: Possible Role of Sleep Deprivation. Basic and clinical neuroscience. vol 9. issue 5. 2020-10-01. PMID:30719245. |
tau pathology of alzheimer disease: possible role of sleep deprivation. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yu-Wei Zhang, Xiao-Qian Li, Wen-Fei Tan, Bo Fang, Hong M. Postoperative 24-h Acute Sleep Deprivation Improves Learning and Memory Through Inhibition of Tau Phosphorylation in the Hippocampal Neurons of Splenectomized Rats. Nature and science of sleep. vol 12. 2020-09-28. PMID:32904483. |
postoperative 24-h acute sleep deprivation improves learning and memory through inhibition of tau phosphorylation in the hippocampal neurons of splenectomized rats. |
2020-09-28 |
2023-08-13 |
rat |
| Yu-Wei Zhang, Xiao-Qian Li, Wen-Fei Tan, Bo Fang, Hong M. Postoperative 24-h Acute Sleep Deprivation Improves Learning and Memory Through Inhibition of Tau Phosphorylation in the Hippocampal Neurons of Splenectomized Rats. Nature and science of sleep. vol 12. 2020-09-28. PMID:32904483. |
as tau pathology is involved in impaired postoperative learning and memory in rats, we attempted to identify the possible mechanisms by which tau pathology affects postoperative sleep deprivation. |
2020-09-28 |
2023-08-13 |
rat |
| Nicolas R Barthélemy, Haiyan Liu, William Lu, Paul T Kotzbauer, Randall J Bateman, Brendan P Luce. Sleep Deprivation Affects Tau Phosphorylation in Human Cerebrospinal Fluid. Annals of neurology. vol 87. issue 5. 2020-07-23. PMID:32057125. |
sleep deprivation affects tau phosphorylation in human cerebrospinal fluid. |
2020-07-23 |
2023-08-13 |
human |