| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhengyun Han, Xingmao Yang, Shuiqing Huan. Sleep deprivation: A risk factor for the pathogenesis and progression of Alzheimer's disease. Heliyon. vol 10. issue 7. 2024-04-16. PMID:38623196. |
recent research has demonstrated the potential involvement of sleep deprivation in both the pathogenesis and progression of ad through glial cell activation, the glial lymphatic system, orexin system, circadian rhythm system, inflammation, and the gut microbiota. |
2024-04-16 |
2024-04-18 |
Not clear |
| Joana Dopp, Antonio Ortega, Kristofer Davie, Suresh Poovathingal, El-Sayed Baz, Sha Li. Single-cell transcriptomics reveals that glial cells integrate homeostatic and circadian processes to drive sleep-wake cycles. Nature neuroscience. 2024-01-24. PMID:38263460. |
the sleep-wake cycle and sleep drive level affect the expression of clock gene regulators in glia, and disrupting clock genes specifically in glia impairs homeostatic sleep rebound after sleep deprivation. |
2024-01-24 |
2024-01-26 |
drosophila_melanogaster |
| Marcio Henrique Mello da Luz, Jessica Monteiro Volejnik Pino, Marcos Mônico-Neto, Priscila Nicolicht de Amorim, Hanna Karen Moreira Antunes, Marimelia Aparecida Porcionatto, Kil Sun Le. Sleep deprivation modulates APOE and LDL receptor-related protein 1 through thyroid hormone T4 and impairs Aβ clearance in hippocampus of rats. Biochimica et biophysica acta. Molecular basis of disease. 2023-05-03. PMID:37137431. |
considering that lrp1 and ldl-r are important for aβ clearance, sleep deprivation might also affect the degree of participation of glia in aβ clearance, and consequently, turnover of aβ in the brain. |
2023-05-03 |
2023-08-14 |
rat |
| Stephane Dissel, Laurent Seugnet, Matthew S Thimgan, Neal Silverman, Veena Angadi, Pamela V Thacher, Melissa M Burnham, Paul J Sha. Differential activation of immune factors in neurons and glia contribute to individual differences in resilience/vulnerability to sleep disruption. Brain, behavior, and immunity. vol 47. 2016-03-23. PMID:25451614. |
these data indicate that various factors within glia or neurons can contribute to individual differences in resilience/vulnerability to sleep deprivation. |
2016-03-23 |
2023-08-13 |
Not clear |
| Stephane Dissel, Laurent Seugnet, Matthew S Thimgan, Neal Silverman, Veena Angadi, Pamela V Thacher, Melissa M Burnham, Paul J Sha. Differential activation of immune factors in neurons and glia contribute to individual differences in resilience/vulnerability to sleep disruption. Brain, behavior, and immunity. vol 47. 2016-03-23. PMID:25451614. |
specifically, metchnikowin (mtk), drosocin (dro) and attacin (att) transcript levels seemed to be differentially increased by sleep deprivation in glia (mtk), neurons (dro) or primarily in the head fat body (att). |
2016-03-23 |
2023-08-13 |
Not clear |
| Laurent Seugnet, Yasuko Suzuki, Gabriel Merlin, Laura Gottschalk, Stephen P Duntley, Paul J Sha. Notch signaling modulates sleep homeostasis and learning after sleep deprivation in Drosophila. Current biology : CB. vol 21. issue 10. 2011-09-16. PMID:21549599. |
importantly, the expression in glia of the intracellular domain of notch, a dominant activated form of the receptor, is sufficient to prevent learning deficits after sleep deprivation. |
2011-09-16 |
2023-08-12 |
drosophila_melanogaster |
| Ganesh Baskey, Abhishek Singh, Rakhi Sharma, Birendra Nath Mallic. REM sleep deprivation-induced noradrenaline stimulates neuronal and inhibits glial Na-K ATPase in rat brain: in vivo and in vitro studies. Neurochemistry international. vol 54. issue 1. 2009-04-24. PMID:19013490. |
the brain contains neurons as well as glia and both possess na-k atpase, however, it was not known if rem sleep deprivation affects the enzyme in both types of cells identically. |
2009-04-24 |
2023-08-12 |
rat |
| Manuel Sánchez-Alavez, Bruno Conti, Gianluca Moroncini, José R Criad. Contributions of neuronal prion protein on sleep recovery and stress response following sleep deprivation. Brain research. vol 1158. 2007-10-12. PMID:17570349. |
in order to gain insights on the function of the cellular prion protein (prp(c)) sleep and the levels of the stress hormones corticosterone (cort) and the adrenocorticotropic hormone (acth) before and after sleep deprivation (sd) were compared in two wild type (wt) mice strains and the following three prp(c) transgenic lines: mice null for prp(c) (mprp(0/0)) and mice with specific and central expression of prp in neurons (nse-hprp/mprp(0/0)) or in glia cells (gfap-hprp/mprp(0/0)). |
2007-10-12 |
2023-08-12 |
mouse |
| V A Klenikova, N P Taranov. [ATPase activity in neurons and glial cells of the brain of the rat after REM-sleep deprivation (cytophotometric study)]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 74. issue 4. 1988-09-06. PMID:2969342. |
the findings can be due to the changes in excitability of the neurons and depolarization of glia during the sleep deprivation. |
1988-09-06 |
2023-08-11 |
rat |