| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tsan-Ju Chen, Dean-Chuan Wang, Pei-Chun Liu, Hui-Shan Hung, Tsung-Lin Chen. Enhanced expression of activity-regulated cytoskeleton-associated protein in the medial prefrontal cortex is involved in working memory performance. The Kaohsiung journal of medical sciences. 2024-04-16. PMID:38623867. |
a memory-related protein arc (activity-regulated cytoskeleton-associated protein) is implicated in long-term memory consolidation. |
2024-04-16 |
2024-04-18 |
rat |
| Rosa Savino, Anna Nunzia Polito, Gabriella Marsala, Antonio Ventriglio, Melanie Di Salvatore, Maria Ida De Stefano, Anna Valenzano, Luigi Marinaccio, Antonello Bellomo, Giuseppe Cibelli, Marcellino Monda, Vincenzo Monda, Antonietta Messina, Rita Polito, Marco Carotenuto, Giovanni Messin. Agomelatine: A Potential Multitarget Compound for Neurodevelopmental Disorders. Brain sciences. vol 13. issue 5. 2023-05-27. PMID:37239206. |
agm would increase the expression of the cytoskeleton-associated protein (arc) in the prefrontal cortex, with optimization of learning, long-term memory consolidation, and improved survival of neurons. |
2023-05-27 |
2023-08-14 |
Not clear |
| Medha Kaushik, Pooja Kaushik, Suhel Parve. Memory Related Molecular Signatures: The Pivots for Memory Consolidation and Alzheimer's Related Memory Decline. Ageing research reviews. 2022-02-01. PMID:35104629. |
research on learning and memory has identified several molecular signatures such as protein kinase m zeta (pkmζ), calcium/calmodulin-dependent protein kinase ii (camkii), brain-derived neurotrophic factor (bdnf), camp-response element binding protein (creb), activity-regulated cytoskeleton-associated protein (arc) crucial for the maintenance and stabilization of long-term memory in the brain. |
2022-02-01 |
2023-08-13 |
Not clear |
| Jayme R McReynolds, Maria B Carreira, Christa K McIntyr. Post-training intra-basolateral complex of the amygdala infusions of clenbuterol enhance memory for conditioned place preference and increase ARC protein expression in dorsal hippocampal synaptic fractions. Neurobiology of learning and memory. vol 185. 2021-11-22. PMID:34648950. |
arc is an immediate early gene whose mrna is localized to the dendrites and is necessary for hippocampus-dependent long-term potentiation and long-term memory formation. |
2021-11-22 |
2023-08-13 |
Not clear |
| Jayme R McReynolds, Maria B Carreira, Christa K McIntyr. Post-training intra-basolateral complex of the amygdala infusions of clenbuterol enhance memory for conditioned place preference and increase ARC protein expression in dorsal hippocampal synaptic fractions. Neurobiology of learning and memory. vol 185. 2021-11-22. PMID:34648950. |
additionally, the necessity of increased hippocampal arc protein expression was also examined for long-term memory formation of the cpp task. |
2021-11-22 |
2023-08-13 |
Not clear |
| Jayme R McReynolds, Maria B Carreira, Christa K McIntyr. Post-training intra-basolateral complex of the amygdala infusions of clenbuterol enhance memory for conditioned place preference and increase ARC protein expression in dorsal hippocampal synaptic fractions. Neurobiology of learning and memory. vol 185. 2021-11-22. PMID:34648950. |
furthermore, immediate post-training intra-dorsal hippocampal infusions of arc antisense oligodeoxynucleotides (odns), which reduce arc protein expression, prevented long-term memory formation for the cpp task. |
2021-11-22 |
2023-08-13 |
Not clear |
| Konstanze Simbriger, Inês S Amorim, Gilliard Lach, Kleanthi Chalkiadaki, Stella Kouloulia, Seyed Mehdi Jafarnejad, Arkady Khoutorsky, Christos G Gkogka. Uncovering memory-related gene expression in contextual fear conditioning using ribosome profiling. Progress in neurobiology. vol 197. 2021-06-11. PMID:32860876. |
herein, using the ribosome profiling methodology, we show that in male mice an immediate shock, which does not lead to ltm formation, elicits pervasive translational and transcriptional changes in the expression of immediate early genes (iegs) in dorsal hippocampus (such as fos and arc), a fact which has been disregarded by the majority of cfc studies. |
2021-06-11 |
2023-08-13 |
mouse |
| Katy Pilarzyk, Jennifer Klett, Edsel A Pena, Latarsha Porcher, Abigail J Smith, Michy P Kell. Loss of Function of Phosphodiesterase 11A4 Shows that Recent and Remote Long-Term Memories Can Be Uncoupled. Current biology : CB. vol 29. issue 14. 2020-07-10. PMID:31303492. |
measurement of a surrogate marker of neuronal activation (i.e., arc mrna) suggests the recent ltm deficits observed in pde11 knockout mice correspond with decreased activation of ventral ca1 relative to wild-type littermates. |
2020-07-10 |
2023-08-13 |
mouse |
| Nicholas A Heroux, Brittany F Osborne, Lauren A Miller, Malak Kawan, Katelyn N Buban, Jeffrey B Rosen, Mark E Stanto. Differential expression of the immediate early genes c-Fos, Arc, Egr-1, and Npas4 during long-term memory formation in the context preexposure facilitation effect (CPFE). Neurobiology of learning and memory. vol 147. 2019-09-09. PMID:29222058. |
differential expression of the immediate early genes c-fos, arc, egr-1, and npas4 during long-term memory formation in the context preexposure facilitation effect (cpfe). |
2019-09-09 |
2023-08-13 |
rat |
| Oleksii Nikolaienko, Sudarshan Patil, Maria Steene Eriksen, Clive R Bramha. Arc protein: a flexible hub for synaptic plasticity and cognition. Seminars in cell & developmental biology. vol 77. 2018-12-11. PMID:28890419. |
neuronal activity-induced expression of the immediate early protein, arc, is critical for long-term potentiation and depression of synaptic transmission, homeostatic synaptic scaling, and adaptive functions such as long-term memory formation. |
2018-12-11 |
2023-08-13 |
Not clear |
| Kioko Guzmán-Ramos, Archana Venkataraman, Jean-Pascal Morin, Daniel Osorio-Gómez, Federico Bermúdez-Ratton. Differential requirement of de novo Arc protein synthesis in the insular cortex and the amygdala for safe and aversive taste long-term memory formation. Behavioural brain research. vol 342. 2018-08-24. PMID:29326059. |
differential requirement of de novo arc protein synthesis in the insular cortex and the amygdala for safe and aversive taste long-term memory formation. |
2018-08-24 |
2023-08-13 |
Not clear |
| Kioko Guzmán-Ramos, Archana Venkataraman, Jean-Pascal Morin, Daniel Osorio-Gómez, Federico Bermúdez-Ratton. Differential requirement of de novo Arc protein synthesis in the insular cortex and the amygdala for safe and aversive taste long-term memory formation. Behavioural brain research. vol 342. 2018-08-24. PMID:29326059. |
the ieg-encoded protein arc (activity regulated cytoskeletal-associated protein) has been widely implicated in long-term memory formation and stabilization. |
2018-08-24 |
2023-08-13 |
Not clear |
| Kioko Guzmán-Ramos, Archana Venkataraman, Jean-Pascal Morin, Daniel Osorio-Gómez, Federico Bermúdez-Ratton. Differential requirement of de novo Arc protein synthesis in the insular cortex and the amygdala for safe and aversive taste long-term memory formation. Behavioural brain research. vol 342. 2018-08-24. PMID:29326059. |
conversely, blocking arc synthesis within the amy impaired cta consolidation but had no effect on st long-term memory formation. |
2018-08-24 |
2023-08-13 |
Not clear |
| Craig Myrum, Sudheer Giddaluru, Kaya Jacobsen, Thomas Espeseth, Lars Nyberg, Astri J Lundervold, Jan Haavik, Lars-Göran Nilsson, Ivar Reinvang, Vidar M Steen, Stefan Johansson, Karin Wibrand, Stephanie Le Hellard, Clive R Bramha. Common variants in the ARC gene are not associated with cognitive abilities. Brain and behavior. vol 5. issue 10. 2016-08-23. PMID:26516611. |
the activity-regulated cytoskeleton-associated (arc) gene encodes a protein that is critical for the consolidation of synaptic plasticity and long-term memory formation. |
2016-08-23 |
2023-08-13 |
human |
| Micol Tomaiuolo, Cynthia Katche, Haydee Viola, Jorge H Medin. Evidence of Maintenance Tagging in the Hippocampus for the Persistence of Long-Lasting Memory Storage. Neural plasticity. vol 2015. 2016-04-19. PMID:26380116. |
the proposed maintenance tagging has several characteristics: (1) the tag is transient and time-dependent; (2) it sets in a late critical time window after an aversive training which induces a short-lasting ltm; (3) exposing rats to a novel environment specifically within this tag time window enables the consolidation to a long-lasting ltm; (4) a familiar environment exploration was not effective; (5) the effect of novelty on the promotion of memory persistence requires dopamine d1/d5 receptors and arc expression in the dorsal hippocampus. |
2016-04-19 |
2023-08-13 |
rat |
| Caroline L Wee, Shaun Teo, Nicodemus E Oey, Graham D Wright, Hendrika M A VanDongen, Antonius M J VanDonge. Nuclear Arc Interacts with the Histone Acetyltransferase Tip60 to Modify H4K12 Acetylation(1,2,3). eNeuro. vol 1. issue 1. 2015-10-14. PMID:26464963. |
arc is an immediate-early gene whose genetic ablation selectively abrogates long-term memory, indicating a critical role in memory consolidation. |
2015-10-14 |
2023-08-13 |
rat |
| Bonnie R Fletcher, Gordon S Hill, Jeffrey M Long, Michela Gallagher, Matthew L Shapiro, Peter R Rap. A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging. Neurobiology of learning and memory. vol 115. 2015-08-04. PMID:25151943. |
expression of the immediate-early gene arc is necessary for normal long-term memory, and although experience dependent arc transcription is reportedly reduced in the aged rat hippocampus, it has not been clear whether this effect is an invariant consequence of growing older, or a finding linked specifically to age-related memory impairment. |
2015-08-04 |
2023-08-13 |
rat |
| Anna G Orr, Edward C Hsiao, Max M Wang, Kaitlyn Ho, Daniel H Kim, Xin Wang, Weikun Guo, Jing Kang, Gui-Qiu Yu, Anthony Adame, Nino Devidze, Dena B Dubal, Eliezer Masliah, Bruce R Conklin, Lennart Muck. Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. Nature neuroscience. vol 18. issue 3. 2015-04-20. PMID:25622143. |
conditional genetic removal of these receptors enhanced long-term memory in young and aging mice and increased the levels of arc (also known as arg3.1), an immediate-early gene that is required for long-term memory. |
2015-04-20 |
2023-08-13 |
mouse |
| Jayme R McReynolds, Crystal M Holloway-Erickson, Tulja U Parmar, Christa K McIntyr. Corticosterone-induced enhancement of memory and synaptic Arc protein in the medial prefrontal cortex. Neurobiology of learning and memory. vol 112. 2015-02-09. PMID:24603007. |
blockade of arc protein expression significantly impaired memory, indicating that the protein is necessary in the mpfc for long-term memory formation. |
2015-02-09 |
2023-08-12 |
rat |
| Ditte Z Christensen, Morten S Thomsen, Jens D Mikkelse. Reduced basal and novelty-induced levels of activity-regulated cytoskeleton associated protein (Arc) and c-Fos mRNA in the cerebral cortex and hippocampus of APPswe/PS1ΔE9 transgenic mice. Neurochemistry international. vol 63. issue 1. 2013-12-27. PMID:23598246. |
activity-regulated cytoskeletal-associated protein (arc) and c-fos are immediate early gene (ieg) products induced by novelty in the hippocampus and involved in the consolidation of synaptic plasticity and long-term memory. |
2013-12-27 |
2023-08-12 |
mouse |