| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alessandro D Genazzani, Christian Battipaglia, Laura Rusce, Greta Prampolini, Claudia Aio, Francesco Ricciardiello, Martina Foschi, Alessandra Sponzilli, Elisa Semprini, Tabatha Petrill. Alpha lipoic acid administration improved both peripheral sensitivity to insulin and liver clearance of insulin reducing potential risk of diabetes and nonalcoholic fatty liver disease in overweight/obese PCOS patients. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 40. issue 1. 2024-04-16. PMID:38622970. |
to evaluate the effects of alpha lipoic acid (ala) on hormonal and metabolic parameters in a group of overweight/obese polycystic ovary syndrome (pcos) patients. |
2024-04-16 |
2024-04-18 |
Not clear |
| Estefany Rengifo, Juan D Rios-Mera, Patricia Huamaní, Rafael Vela-Paredes, Jessy Vásquez, Erick Saldaña, Raúl Siche, Fernando Tell. Fish Burgers Fortified with Microencapsulated Sacha Inchi Oil: Effects on Technological and Sensory Properties. Foods (Basel, Switzerland). vol 13. issue 7. 2024-04-13. PMID:38611310. |
the long-chain omega-3 fatty acids alpha linolenic acid (ala), eicosapentaenoic acid (epa), and docosahexaenoic acid (dha) have proven health benefits, but it is not common to find them together in a processed food product. |
2024-04-13 |
2024-04-15 |
Not clear |
| Yimeng Zhang, Ya Zhou, Xiaohong Li, Xu Pan, Ju Bai, Yijin Chen, Zhenyang Lai, Qiang Chen, Feng Ma, Yong Don. Small-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation. Stem cell research & therapy. vol 15. issue 1. 2024-04-08. PMID:38589882. |
in hematopoiesis, ala (alpha lipoic acid) is reported to inhibit neutrophil lineage determination by targeting transcription factor elk1 in granulocyte-monocyte progenitors via splicing factor sf3b1. |
2024-04-08 |
2024-04-11 |
human |
| Hatice Şiyzen Çoban, Nazlı Çil, Elif Önder, Gülçin Abban Met. Anti-cancer effects of alpha lipoic acid, cisplatin and paclitaxel combination in the OVCAR-3 ovarian adenocarcinoma cell line. Molecular biology reports. vol 51. issue 1. 2024-04-05. PMID:38578399. |
one of the major challenges in treating ovarian cancer with chemotherapy is managing the resistance developed by cancer cells to drugs, while also minimizing the side effects caused by these agents in the present study, we aimed to examine the effects of a combination of alpha lipoic acid (ala), with cisplatin and paclitaxel in ovarian cancer(ovcar-3). |
2024-04-05 |
2024-04-07 |
Not clear |
| Ramanachary Namoju, Kavitha N Chilak. Protective effect of alpha‑lipoic acid against in utero cytarabine exposure-induced hepatotoxicity in rat female neonates. Naunyn-Schmiedeberg's archives of pharmacology. 2024-03-09. PMID:38459988. |
alpha lipoic acid (ala) is a natural antioxidant reported to offer protection against hepatotoxicity induced by various pathological conditions, drugs, or chemicals. |
2024-03-09 |
2024-03-12 |
rat |
| Madeline C Tompach, Charlotte K Gridley, Sida Li, John M Clark, Yeonhwa Park, Alicia R Timme-Larag. Comparing the effects of developmental exposure to alpha lipoic acid (ALA) and perfluorooctanesulfonic acid (PFOS) in zebrafish (Danio rerio). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-03-03. PMID:38432440. |
comparing the effects of developmental exposure to alpha lipoic acid (ala) and perfluorooctanesulfonic acid (pfos) in zebrafish (danio rerio). |
2024-03-03 |
2024-03-06 |
zebrafish |
| Madeline C Tompach, Charlotte K Gridley, Sida Li, John M Clark, Yeonhwa Park, Alicia R Timme-Larag. Comparing the effects of developmental exposure to alpha lipoic acid (ALA) and perfluorooctanesulfonic acid (PFOS) in zebrafish (Danio rerio). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-03-03. PMID:38432440. |
alpha lipoic acid (ala) is a dietary supplement that has been used to treat a wide range of diseases including obesity and diabetes and have lipid-lowering effects, making it a potential candidate for mitigating dyslipidemia resulting from exposures to the per- and polyfluoroalkyl substance (pfas) family member perfluorooctanesulfonic acid (pfos). |
2024-03-03 |
2024-03-06 |
zebrafish |
| Alexandros Tsoupras, Donal Moran, Katie Shiels, Sushanta Kumar Saha, Ibrahim M Abu-Reidah, Raymond H Thomas, Shane Redfer. Enrichment of Whole-Grain Breads with Food-Grade Extracted Apple Pomace Bioactives Enhanced Their Anti-Inflammatory, Antithrombotic and Anti-Oxidant Functional Properties. Antioxidants (Basel, Switzerland). vol 13. issue 2. 2024-02-24. PMID:38397823. |
structural analysis by lcms showed that the pl-bioactives from all these sources (ap and the bio-functional breads) are rich in bioactive unsaturated fatty acids (ufa), especially in the omega-9 oleic acid (oa; 18:1n9), the omega-3 alpha linolenic acid (ala; 18:n3) and the omega-6 linoleic acid (la; 18:2n6), which further supports their strong anti-inflammatory and antithrombotic properties. |
2024-02-24 |
2024-02-26 |
human |
| Mario B Prado, Karen Joy B Adia. Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis. Canadian journal of diabetes. 2024-02-13. PMID:38295879. |
the purpose of this work was to summarize the available evidence about the efficacy and safety of alpha lipoic acid (ala) and gamma linolenic acid (gla) in the management of dn. |
2024-02-13 |
2024-02-15 |
Not clear |
| Giuseppina Porcaro, Antonio Simone Laganà, Isabella Neri, Cesare Aragon. The Association of High-Molecular-Weight Hyaluronic Acid (HMWHA), Alpha Lipoic Acid (ALA), Magnesium, Vitamin B6, and Vitamin D Improves Subchorionic Hematoma Resorption in Women with Threatened Miscarriage: A Pilot Clinical Study. Journal of clinical medicine. vol 13. issue 3. 2024-02-10. PMID:38337402. |
the association of high-molecular-weight hyaluronic acid (hmwha), alpha lipoic acid (ala), magnesium, vitamin b6, and vitamin d improves subchorionic hematoma resorption in women with threatened miscarriage: a pilot clinical study. |
2024-02-10 |
2024-02-12 |
Not clear |
| Giuseppina Porcaro, Antonio Simone Laganà, Isabella Neri, Cesare Aragon. The Association of High-Molecular-Weight Hyaluronic Acid (HMWHA), Alpha Lipoic Acid (ALA), Magnesium, Vitamin B6, and Vitamin D Improves Subchorionic Hematoma Resorption in Women with Threatened Miscarriage: A Pilot Clinical Study. Journal of clinical medicine. vol 13. issue 3. 2024-02-10. PMID:38337402. |
background-we evaluated whether the oral intake of high-molecular-weight hyaluronic acid (hmwha) in association with alpha lipoic acid (ala), magnesium, vitamin b6, and vitamin d can improve the resorption of subchorionic hematoma in cases of threatened miscarriage. |
2024-02-10 |
2024-02-12 |
Not clear |
| Patrícia Rodrigues, Gabriela Buzatti Cassanego, Diulle Spat Peres, Fernanda Tibolla Viero, Sabrina Qader Kudsi, Náthaly Andrighetto Ruviaro, Karine de Vargas Aires, Valério Marques Portela, Liliane De Freitas Bauermann, Gabriela Trevisa. Alpha-lipoic acid reduces nociception by reducing oxidative stress and neuroinflammation in a model of complex regional pain syndrome type I in mice. Behavioural brain research. 2023-12-01. PMID:38040057. |
antioxidants, such as alpha lipoic acid (ala), have shown a therapeutic potential for crps-i pain control. |
2023-12-01 |
2023-12-10 |
mouse |
| Takehiro Himaki, Kazuki Han. Effects of alpha lipoic acid treatment during in vitro maturation on the development of porcine somatic cell nuclear transfer embryos. Animal science journal = Nihon chikusan Gakkaiho. vol 94. issue 1. 2023-12-01. PMID:38031165. |
we investigated the effects of alpha lipoic acid (ala) treatment during the in vitro maturation (ivm) period on the porcine somatic cell nuclear transfer (scnt) embryo production. |
2023-12-01 |
2023-12-10 |
Not clear |
| Mahdi Vajdi, Nooshin Noshadi, Shirin Hassanizadeh, Atefeh Bonyadian, Hooria Seyedhosseini-Ghaheh, Gholamreza Askar. The effects of alpha lipoic acid (ALA) supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Frontiers in cardiovascular medicine. vol 10. 2023-11-09. PMID:37942070. |
the effects of alpha lipoic acid (ala) supplementation on blood pressure in adults: a grade-assessed systematic review and dose-response meta-analysis of randomized controlled trials. |
2023-11-09 |
2023-11-20 |
Not clear |
| Mahdi Vajdi, Nooshin Noshadi, Shirin Hassanizadeh, Atefeh Bonyadian, Hooria Seyedhosseini-Ghaheh, Gholamreza Askar. The effects of alpha lipoic acid (ALA) supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Frontiers in cardiovascular medicine. vol 10. 2023-11-09. PMID:37942070. |
there have been various clinical studies on the effect of alpha lipoic acid (ala) supplementation on blood pressure (bp), but the findings from these are contradictory. |
2023-11-09 |
2023-11-20 |
Not clear |
| Walaa El-Houseiny, Ahmed H Arisha, Mohamed M M Metwally, Abdel-Wahab A Abdel-Warith, Elsayed M Younis, Simon J Davies, Bayan A Hassan, Yasmina M Abd-Elhaki. Alpha-lipoic acid suppresses gibberellic acid nephrotoxicity in Nile tilapia (Oreochromis niloticus) via modulating oxidative stress, inflammation, cytokine production, and apoptosis. Pesticide biochemistry and physiology. vol 196. 2023-11-09. PMID:37945227. |
recently, alpha lipoic acid (ala) has drawn much interest due to its antioxidant properties. |
2023-11-09 |
2023-11-20 |
cat |
| Wei Wang, Dandan Zhang, Lei Sun, Zihao Zhang, Yiwen Zhang, Yongteng Zhang, Yunhai Zhang, Mianqun Zhan. Alpha-lipoic acid supplementation reverses the declining quality of oocytes exposed to cyclophosphamide. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-10-14. PMID:37838213. |
as a cofactor of mitochondrial multienzyme complexes, alpha lipoic acid (ala) is well known for its antioxidant characteristics, which operate directly on the scavenging of reactive oxygen species (ros) and indirectly on the intracellular recycling of other antioxidants. |
2023-10-14 |
2023-11-08 |
Not clear |
| Mohammed Abdullah Ali, Ansam Naji Alhassani, Badraldin Kareem Hama. Impacts of trelagliptin and remogliflozin alone and in combination with Alpha Lipoic Acid on cardiac function in streptozotocin-induced diabetes mellitus in rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 9. 2023-10-09. PMID:37807327. |
this study investigated the effects of trelagliptin and remogliflozin, alone and in combination with alpha lipoic acid (ala), on cardiac biomarkers in diabetic cardiomyopathy (dcm). |
2023-10-09 |
2023-10-15 |
rat |
| Elif Önder, Nazlı Çil, Mücahit Seçme, Gülçin Abban Met. Effect of Alpha Lipoic Acid on Epithelial Mesenchymal Transition in SKOV-3 Cells. Gene. 2023-10-09. PMID:37813206. |
it has been suggested that alpha lipoic acid (ala), a natural antioxidant lipophilic compound, reduces the oxidative stress by causing apoptosis and inhibition of proliferation of cell in cancer cells. |
2023-10-09 |
2023-10-15 |
Not clear |
| Anja Divković, Zinaida Karasalihović, Ivana Rumora Samarin, Damir Sabitović, Kristina Radić, Nikolina Golub, Lovorka Vujić, Marija Grdić Rajković, Dubravka Vitali Čep. Effect of Alpha Lipoic Acid Supplementation on Oxidative Stress and Lipid Parameters in Women Diagnosed with Low-Grade Squamous Intraepithelial Lesions (LSILs): A Double-Blind, Randomized, Placebo-Controlled Trial. Antioxidants (Basel, Switzerland). vol 12. issue 9. 2023-09-28. PMID:37759972. |
limited scientific evidence shows that alpha lipoic acid (ala) can induce regression rates of low-grade squamous intraepithelial lesions (lsils), but the mechanisms of these effects have not been elucidated. |
2023-09-28 |
2023-10-07 |
human |