| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Sabriye Karadenizli Ta\\xc5\\x9fkin, Deniz \\xc5\\x9eahin, Fazilet Dede, Zehra Seda \\xc3\\x9cnal Halbuto\\xc4\\x9fullari, Mehmet Sarihan, Sema Kurnaz \\xc3\\x96zbek, \\xc3\\x96zg\\xc3\\xbcr Do\\xc4\\x9fa \\xc3\\x96zsoy, Murat Kasap, Yusufhan Yazir, Nurbay Ate\\xc5\\x9. Endoplasmic reticulum stress produced by Thapsigargin affects the occurrence of spike-wave discharge by modulating unfolded protein response pathways and activating immune responses in a dose-dependent manner. European journal of pharmacology. 2024-04-26. PMID:38670446.' |
in cortex and thalamus tissues, grp78, erp57, gad153 protein changes (western blot), eif2ak3, xbp-1, atf6, cacna1h mrna expressions (rt-pcr), nf-κb and tnf-α levels (elisa) were measured. |
2024-04-26 |
2024-04-29 |
rat |
| Yining Lei, Manqin Li, Xinran Liu, Lu Zhang, Ruyi Zhang, Fei Ca. Nerolidol rescues hippocampal injury of diabetic rats through inhibiting NLRP3 inflammasome and regulation of MAPK/AKT pathway. BioFactors (Oxford, England). 2024-04-16. PMID:38624190. |
western blot was used to detect apoptosis (bcl-2, bax, and cleaved-caspase-3); synapses (postsynaptic densifying protein 95, syn1, and synaptophysin); mitochondria (drp1, opa1, mfn1, and mfn2); er (grp78, atf6, chop, and caspase-12); nlrp3 inflammasome (nlrp3, asc, and caspase-1); inflammatory cytokines (il-18, il-1β, and tnf-α); akt (p-akt); and mitogen-activated protein kinase (mapk) pathway (p-erk, p-p38, and p-jnk) related protein expression. |
2024-04-16 |
2024-04-18 |
rat |
| Xiaogang Huang, Xiongzhi He, Rongxian Qiu, Xuemei Xie, Fengfeng Zheng, Feihua Chen, Zhenting H. Unfolded protein response inhibits KAT2B/MLKL-mediated necroptosis of hepatocytes by promoting BMI1 level to ubiquitinate KAT2B. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-06-19. PMID:37333449. |
the expression levels of bmi1, kat2b, and proteins related to upr (p-eif2α, eif2α, atf4, and atf6), nf-κb (p65 and p-p65), apoptosis (cleaved caspase-3, bcl-2, and bax) and necroptosis (p-mlkl and mlkl) were determined by western blot. |
2023-06-19 |
2023-08-14 |
Not clear |
| Zhao Tang, Wenjing Du, Fei Xu, Xianjun Sun, Wenjing Chen, Jie Cui, Weifeng Tang, Fangyong Yang, Fangzhou Teng, Jinpei Lin, Baojun Liu, Jingcheng Don. Icariside II enhances cisplatin-induced apoptosis by promoting endoplasmic reticulum stress signalling in non-small cell lung cancer cells. International journal of biological sciences. vol 18. issue 5. 2022-03-28. PMID:35342361. |
the western blot results revealed that is activated endoplasmic reticulum (er) stress, including three branches of upr signalling, perk, ire1 and atf6, and the downstream perk-eif2α-atf4-chop pathway, thus potentiating the apoptosis induced by cisplatin. |
2022-03-28 |
2023-08-13 |
mouse |
| Xiaoqing Yi, Xuan Cai, Sisi Wang, Yanfeng Xia. Mechanisms of impaired pancreatic β‑cell function in high‑fat diet‑induced obese mice: The role of endoplasmic reticulum stress. Molecular medicine reports. vol 21. issue 5. 2021-02-16. PMID:32323766. |
in vitro, ers was induced by palmitate (pa) in ins‑1 cells, and the protein expression of atf6, and mrna expression of atf6 and insulin were examined via western blot and quantitative pcr (qpcr) analyses, respectively. |
2021-02-16 |
2023-08-13 |
mouse |
| Weike Mao, Shuji Fukuoka, Chikao Iwai, Jiahao Liu, Virendra K Sharma, Shey-Shing Sheu, Michael Fu, Chang-seng Lian. Cardiomyocyte apoptosis in autoimmune cardiomyopathy: mediated via endoplasmic reticulum stress and exaggerated by norepinephrine. American journal of physiology. Heart and circulatory physiology. vol 293. issue 3. 2007-10-19. PMID:17545481. |
myocyte apoptosis was determined by terminal deoxytransferase-mediated dutp nick-end labeling and caspase-3 activity, whereas camkii, mapk family (jnk, p38, erk), and er stress signals (atf6, grp78, chop, caspase-12) were measured by western blot, immunohistochemistry, and kinase activity assay. |
2007-10-19 |
2023-08-12 |
Not clear |