| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammad S El-Wetidy, Mohamad I Rady, Islam Rady, Hamed Hela. Urolithin A affects cellular migration and modulates matrix metalloproteinase expression in colorectal cancer cells. Cell biochemistry and function. vol 42. issue 3. 2024-04-16. PMID:38622949. |
the western blot analysis investigation revealed that ua inhibits cellular metastasis by lowering the expression levels of matrix metalloproteinases 1 and 2 (mmp1 and mmp2) by more than 43% and 41% (p < .001) in ht29, 28% and 149% (p < .001) in sw480, and 90% and 74% (p < .001) in sw620, respectively, at a 100 µm dosage of ua compared to the control. |
2024-04-16 |
2024-04-18 |
Not clear |
| Yi Zhang, Wei-Long Hong, Zhi-Ming Li, Qi-Yu Zhang, Kang Zen. The Mechanism of miR-222 Targets Matrix Metalloproteinase 1 in Regulating Fibroblast Proliferation in Hypertrophic Scars. Aesthetic plastic surgery. vol 45. issue 2. 2021-04-19. PMID:32350561. |
furthermore, qrt-pcr and western blot were employed to detect the matrix metalloproteinase 1 (mmp1) rna/protein after fibroblasts were transfected with the mir-222 mimic/inhibitor. |
2021-04-19 |
2023-08-13 |
Not clear |
| Lokender Kumar, Warren Colomb, John Czerski, Christopher R Cox, Susanta K Sarka. Efficient protease based purification of recombinant matrix metalloprotease-1 in E. coli. Protein expression and purification. vol 148. 2019-03-15. PMID:29626520. |
identity of activated mmp1 was confirmed by western blot using anti-human mmp1 antibodies, whereas the mass was determined to be 43 kd using matrix assisted laser desorption ionization time-of-flight mass spectrometry (maldi tof-ms). |
2019-03-15 |
2023-08-13 |
human |
| Pengfei Feng, Xiaona Li, Weiyi Chen, Rui He, Xiaojun Wan. [Effects of Tumor Necrosis Factor Alpha on the Expression of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinases in Keratoconus Fibroblasts]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 33. issue 6. 2018-06-18. PMID:29714979. |
the aim of this article is to study the effect of tumor necrosis factor alpha(tnf-α)on the expression of matrix metalloproteinases(mmps)and tissue inhibitors of matrix metalloproteinases(timps)in keratoconus fibroblasts in vitro.normal cornea and keratoconus fibroblasts were extracted using enzyme digestion method and were cultured in the medium containing tnf-α(0,10 and 100ng/ml).the expression of mmps proteins in the supernatant of corneal fibroblasts and the expression of timps in the normal cornea and keratoconus fibroblasts were detected by western blot and real-time quantitative polymerase chain reaction respectively.the active form of mmp1 could be detected in the supernatant of keratoconus fibroblasts and upregulated by tnf-α.tnf-αcould increase the protein expression of mmp2,mmp3,mmp9 in the supernatant of keratoconus fibroblasts and decrease the gene expression of timp1,timp2 in keratoconus fibroblasts.the increased mmps and the decreased timps can increase the degradation of the extracellular matrix.tnf-αmay play an important role in the occurrence and development of keratoconus by regulating the expression of mmps/timps. |
2018-06-18 |
2023-08-13 |
Not clear |
| Chanjuan Li, Yuan Zhang, Lisha Tang, Haijun Zhao, Chao Gao, Li Gao, Yugui Cui, Jiayin Li. Expression of factors involved in the regulation of angiogenesis in the full-term human placenta: Effects of in vitro fertilization. Reproductive biology. vol 16. issue 2. 2017-04-06. PMID:27288334. |
the levels of four of them, including vascular endothelial growth factor receptor-3 (vegfr3), basic fibroblast growth factor (bfgf), interferon gamma (ifng) and matrix metalloproteinase 1 (mmp1), were quantified using western blot analysis. |
2017-04-06 |
2023-08-13 |
human |
| Xinyu Shao, Xiaojun Cao, Ge Song, Yuan Zhao, Bimin Sh. Metformin rescues the MG63 osteoblasts against the effect of high glucose on proliferation. Journal of diabetes research. vol 2014. 2014-10-28. PMID:24812633. |
real-time pcr and western blot were performed to compare the expression of collagen i (col i), osteocalcin (ocn), osteoprotegerin (opg), receptor activator for nf- κb ligand (rankl), and metal matrix proteinases 1 and 2 (mmp1, mmp2). |
2014-10-28 |
2023-08-13 |
Not clear |
| Ji-Hong Shi, Hao Guan, Shan Shi, Wei-Xia Cai, Xiao-Zhi Bai, Xiao-Long Hu, Xiao-Bin Fang, Jia-Qi Liu, Ke Tao, Xiong-Xiang Zhu, Chao-Wu Tang, Da-Hai H. Protection against TGF-β1-induced fibrosis effects of IL-10 on dermal fibroblasts and its potential therapeutics for the reduction of skin scarring. Archives of dermatological research. vol 305. issue 4. 2013-10-22. PMID:23321694. |
in this study, human dermal fibroblasts stimulated with tgf-β1 were treated with il-10 to analyze the mrna and some of proteins' expression levels of type i collagen (col1), type iii collagen (col3), alpha-smooth muscle actin (α-sma), matrix metalloproteinase-1 (mmp1), mmp2, mmp8 and tissue inhibitor of metalloproteinase 1 (timp1), timp2 by real-time pcr and western blot, to observe α-sma-positive fibroblasts by immunocytochemistry. |
2013-10-22 |
2023-08-12 |
human |