| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Boyu Li, Limin Ye, Cheng Zhang, Ruofan Liu, Chi Wang, Xiaotian Zhang, Hong Ji, Haibo Y. Effects of glycerol monolaurate on estradiol and follicle-stimulating hormones, offspring quality, and mRNA expression of reproductive-related genes of zebrafish (Danio rerio) females. Fish physiology and biochemistry. 2024-04-16. PMID:38625478. |
these results suggest that gml may stimulate the expression of gnrh2 and gnrh3 by increasing the expression level of kiss1 and kiss2 genes in the hypothalamus, thus promoting the synthesis of fsh and e2. |
2024-04-16 |
2024-04-18 |
zebrafish |
| Christine Horne, Jon Vidar Helvik, Mitchell Stewart Fleming, Per Gunnar Fjelldal, Mariann Eilertse. Mapping the pattern of essential neuroendocrine cells related to puberty and VA opsin expression provides further insight in the photoreceptive regulation of the BPG axis in Atlantic salmon (Salmo salar). Brain, behavior and evolution. 2022-08-03. PMID:35921812. |
neurons positive for gnrh3 are expressed in the olfactory bulb and ventral telencephalon while gnrh2 positive neurons are located dorsally in midbrain tegmentum. |
2022-08-03 |
2023-08-14 |
Not clear |
| Satoshi Ogawa, Naoyuki Yamamoto, Hanako Hagio, Yoshitaka Oka, Ishwar S Parha. Multiple gonadotropin-releasing hormone systems in non-mammalian vertebrates: Ontogeny, anatomy, and physiology. Journal of neuroendocrinology. 2021-12-21. PMID:34931380. |
in other fish species (zebrafish, goldfish and salmon) with only two gnrh paralogs (gnrh2 and gnrh3), the tn- and poa-gnrh3 neuronal types share the same olfactory origin. |
2021-12-21 |
2023-08-13 |
zebrafish |
| Satoshi Imamura, Sung-Pyo Hur, Yuki Takeuchi, Muhammad Badruzzaman, Angka Mahardini, Dinda Rizky, Akihiro Takemur. The mRNA expression patterns of kisspeptins, GnRHs, and gonadotropins in the brain and pituitary gland of a tropical damselfish, Chrysiptera cyanea, during the reproductive cycle. Fish physiology and biochemistry. vol 46. issue 1. 2020-10-23. PMID:31705423. |
quantitative polymerase chain reaction analyses in various brain parts revealed high expression levels of kiss1, kiss2, and gnrh2 in the diencephalon; gnrh2 and gnrh3 in the telencephalon; and fshβ and lhβ in the pituitary. |
2020-10-23 |
2023-08-13 |
Not clear |
| Wenqiang Wang, Jun Chen, Yan Fang, Bin Wang, Qiang Zou, Lei Wang, Wenwen Zhang, Xueying Huang, Haoyue Lv, Chenxiao Zhang, Kai Wan. Identification of gnrh2 and gnrh3 and their expression during brood pouch growth and short-term benzo(a)pyrene exposure in lined seahorse (Hippocampus erectus). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 225. 2020-02-21. PMID:31386905. |
identification of gnrh2 and gnrh3 and their expression during brood pouch growth and short-term benzo(a)pyrene exposure in lined seahorse (hippocampus erectus). |
2020-02-21 |
2023-08-13 |
Not clear |
| Wenqiang Wang, Jun Chen, Yan Fang, Bin Wang, Qiang Zou, Lei Wang, Wenwen Zhang, Xueying Huang, Haoyue Lv, Chenxiao Zhang, Kai Wan. Identification of gnrh2 and gnrh3 and their expression during brood pouch growth and short-term benzo(a)pyrene exposure in lined seahorse (Hippocampus erectus). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 225. 2020-02-21. PMID:31386905. |
to better understand the role of gnrh in brood pouch growth and effects of bap on reproductive endocrine in lined seahorse (hippocampus erectus), gnrh2 and gnrh3 genes were identified. |
2020-02-21 |
2023-08-13 |
Not clear |
| Sheryll Corchuelo, Emanuel R M Martinez, Arno J Butzge, Lucas B Doretto, Juliana M B Ricci, Fernanda N Valentin, Laura S O Nakaghi, Gustavo M Somoza, Rafael H Nóbreg. Characterization of Gnrh/Gnih elements in the olfacto-retinal system and ovary during zebrafish ovarian maturation. Molecular and cellular endocrinology. vol 450. 2018-02-23. PMID:28400274. |
the current study analyzed the presence of gnrh2 and gnrh3, their receptors (gnrhr 1,2,3 and 4) and gnih (gonadotropin inhibitory hormone) transcripts, as well as the gnrh3 protein in the olfactory epithelium (oe), olfactory bulb (ob), retina and ovary during zebrafish ovarian maturation. |
2018-02-23 |
2023-08-13 |
zebrafish |
| Weiting Chen, Shuk-Wa Lau, Yuqin Fan, Rudolf S S Wu, Wei G. Juvenile exposure to bisphenol A promotes ovarian differentiation but suppresses its growth - Potential involvement of pituitary follicle-stimulating hormone. Aquatic toxicology (Amsterdam, Netherlands). vol 193. 2017-12-07. PMID:29055862. |
these effects did not seem to involve the hypothalamus because neither bpa nor e2 altered the expression of kiss1, kiss2, gnrh2 and gnrh3 in the hypothalamus. |
2017-12-07 |
2023-08-13 |
zebrafish |
| ShunLong Meng, LiPing Qiu, GengDong Hu, LiMin Fan, Chao Song, Yao Zheng, Wei Wu, JianHong Qu, DanDan Li, JiaZhang Chen, Pao X. Effects of methomyl on steroidogenic gene transcription of the hypothalamic-pituitary-gonad-liver axis in male tilapia. Chemosphere. vol 165. 2017-04-19. PMID:27643660. |
however, higher concentrations of methomyl (20 and 200 μg/l) disrupted the endocrine system and caused significant increase in the levels of gnrh2, gnrh3, erα, and erβ genes in the hypothalamus, gnrhr and fshβ genes in the pituitary, cyp19a, fshr, and erα genes in the testis, and vtg and erα genes in the liver, and significantly decreased the levels of lhr, star, 3β-hsd, and arα genes in the testis and lhβ gene in the pituitary, leading to changes in sex steroid hormone and vitellogenin levels in the serum and ultimately resulting in reproductive dysfunction in male tilapia. |
2017-04-19 |
2023-08-13 |
Not clear |
| Parvathy Prasad, Satoshi Ogawa, Ishwar S Parha. Serotonin reuptake inhibitor citalopram inhibits GnRH synthesis and spermatogenesis in the male zebrafish. Biology of reproduction. vol 93. issue 4. 2016-07-14. PMID:26157069. |
to elucidate the neuroendocrine mechanisms of ssri-induced reproductive failure, we examined the neuronal association between 5-ht and gnrh (gnrh2 and gnrh3) systems in the male zebrafish. |
2016-07-14 |
2023-08-13 |
zebrafish |
| Parvathy Prasad, Satoshi Ogawa, Ishwar S Parha. Serotonin reuptake inhibitor citalopram inhibits GnRH synthesis and spermatogenesis in the male zebrafish. Biology of reproduction. vol 93. issue 4. 2016-07-14. PMID:26157069. |
double-label immunofluorescence and confocal laser microscopy followed by three-dimensional construction analysis showed close associations between 5-ht fibers with gnrh3 fibers and preoptic-gnrh3 cell bodies, but there was no association with gnrh2 cell bodies and fibers. |
2016-07-14 |
2023-08-13 |
zebrafish |
| Felipe Espigares, Manuel Carrillo, Ana Gómez, Silvia Zanu. The forebrain-midbrain acts as functional endocrine signaling pathway of Kiss2/Gnrh1 system controlling the gonadotroph activity in the teleost fish European sea bass (Dicentrarchus labrax). Biology of reproduction. vol 92. issue 3. 2016-02-22. PMID:25609835. |
to establish the gene expression cascade involved in the action of kisspeptins, the expression of the two sea bass kisspeptin receptor genes (kiss1r and kiss2r) and the three sea bass gnrh genes (gnrh1, gnrh2, and gnrh3) were analyzed in the forebrain-midbrain and the hypothalamus. |
2016-02-22 |
2023-08-13 |
Not clear |
| Yi Ta Shao, Yung Che Tseng, Chia-Hao Chang, Hong Young Yan, Pung Pung Hwang, Bertil Bor. GnRH mRNA levels in male three-spined sticklebacks, Gasterosteus aculeatus, under different reproductive conditions. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 180. 2015-08-21. PMID:25446939. |
moreover, higher gnrh2 mrna levels in the th and higher gnrh3 mrna levels in the t+poa and hypothalamus (hypth) were also found in long-day sham-operated males than in sham-operated fish kept under an inhibitory short day photoperiod. |
2015-08-21 |
2023-08-13 |
chicken |
| Yi Ta Shao, Yung Che Tseng, Chia-Hao Chang, Hong Young Yan, Pung Pung Hwang, Bertil Bor. GnRH mRNA levels in male three-spined sticklebacks, Gasterosteus aculeatus, under different reproductive conditions. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 180. 2015-08-21. PMID:25446939. |
fully breeding males had considerably higher mrna levels of gnrh2 and gnrh3 in the thalamus (th) and in the telencephalon and preoptic area (t+poa), respectively, than post-breeding males. |
2015-08-21 |
2023-08-13 |
chicken |
| H Ando, S Ogawa, Md Shahjahan, T Ikegami, H Doi, A Hattori, I Parha. Diurnal and circadian oscillations in expression of kisspeptin, kisspeptin receptor and gonadotrophin-releasing hormone 2 genes in the grass puffer, a semilunar-synchronised spawner. Journal of neuroendocrinology. vol 26. issue 7. 2015-02-06. PMID:24824153. |
moreover, midbrain gnrh2 gene (gnrh2) but not gnrh1 or gnrh3 genes show a unique semidiurnal oscillation with two peaks at zt6 and zt18 within a day. |
2015-02-06 |
2023-08-13 |
Not clear |
| Sarah M Tuziak, Hélène Volkof. Gonadotrophin-releasing hormone in winter flounder (Pseudopleuronectes americanus): molecular characterization, distribution and effects of fasting. General and comparative endocrinology. vol 184. 2013-09-05. PMID:23298570. |
fasting reduces gnrh2 and gnrh3 mrna expression in the optic tectum/thalamus and hypothalamus, and telencephalon/preoptic area, respectively, compared with fed fish. |
2013-09-05 |
2023-08-12 |
Not clear |
| Takeshi A Onuma, Yonghe Ding, Eytan Abraham, Yonathern Zohar, Hironori Ando, Cunming Dua. Regulation of temporal and spatial organization of newborn GnRH neurons by IGF signaling in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 33. 2011-10-13. PMID:21849542. |
blockage of igf signaling also resulted in an abnormal appearance of gnrh3 neurons outside of the olfactory bulb region, although it did not change the locations of other olfactory neurons, gnrh2 neurons, or brain patterning. |
2011-10-13 |
2023-08-12 |
zebrafish |
| Takeshi A Onuma, Yonghe Ding, Eytan Abraham, Yonathern Zohar, Hironori Ando, Cunming Dua. Regulation of temporal and spatial organization of newborn GnRH neurons by IGF signaling in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 33. 2011-10-13. PMID:21849542. |
here we show that blockage of igf signaling, a central growth-promoting signaling pathway, by the induced expression of a dominant-negative form of igf1 receptor (igf1r) or specific igf1r inhibitors delayed the emergence of gnrh2 neurons in the midbrain and gnrh3 neurons in the olfactory bulb region. |
2011-10-13 |
2023-08-12 |
zebrafish |
| Y Ok. Electrophysiological characteristics of gonadotrophin-releasing hormone 1-3 neurones: insights from a study of fish brains. Journal of neuroendocrinology. vol 22. issue 7. 2010-11-12. PMID:20646172. |
the hypophysiotropic gnrh1 neurones in the preoptic area show episodic spontaneous electrical activities, whereas the extrahypothalamic gnrh2 neurones in the midbrain and gnrh3 neurones in the terminal nerve show regular intrinsic pacemaker activities. |
2010-11-12 |
2023-08-12 |
Not clear |
| Masae Kinoshita, Suguru Kobayashi, Akihisa Urano, Etsuro It. Neuromodulatory effects of gonadotropin-releasing hormone on retinotectal synaptic transmission in the optic tectum of rainbow trout. The European journal of neuroscience. vol 25. issue 2. 2007-04-05. PMID:17284189. |
epscs were increased by application of each of two types of gnrh (gnrh2 and gnrh3) in the trout tectum. |
2007-04-05 |
2023-08-12 |
Not clear |