All Relations between hmgb1 and msc
Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jun Tong, Genhong Yao, Yueqin Chen, Hairong Xie, Xinyu Zheng, Lingyun Sun, Zhenping Huang, Zhenggao Xi. Mesenchymal Stem Cells Regulate Microglial Polarization via Inhibition of the HMGB1/TLR4 Signaling Pathway in Diabetic Retinopathy. Inflammation. 2024-04-16. PMID:38625640. |
overexpression of hmgb1 in microglia reversed the effects of msc treatment, suggesting hmgb1/tlr4 pathway is necessary for mscs' regulatory effects on microglia polarization. |
2024-04-16 |
2024-04-18 |
rat |
Claudia Cristina Biguetti, Franco Cavalla, Elcia Varize Silveira, André Petenuci Tabanez, Carolina Favaro Francisconi, Rumio Taga, Ana Paula Campanelli, Ana Paula Favaro Trombone, Danieli C Rodrigues, Gustavo Pompermaier Garle. HGMB1 and RAGE as Essential Components of Ti Osseointegration Process in Mice. Frontiers in immunology. vol 10. 2020-09-21. PMID:31024546. |
in conclusion, hmgb1 and rage have a marked role in the osseointegration, evidenced by their influence on host inflammatory immune response, which includes macrophages migration and m1/m2 response, msc markers expression, which collectively modulate bone matrix deposition and osseointegration outcome. |
2020-09-21 |
2023-08-13 |
mouse |
S Vogel, V Börger, C Peters, M Förster, P Liebfried, K Metzger, R Meisel, W Däubener, T Trapp, J C Fischer, M Gawaz, R V Sor. Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death. Cell death and differentiation. vol 22. issue 7. 2016-04-08. PMID:25571972. |
moreover, necrotic cardiomyocytic and neuronal cells caused an hmgb1/toll-like receptor-4-dependent inhibition of msc migration towards apoptosis or hgf, while recruitment of monocytes and idc by necrosis or hmgb1 was not affected by apoptotic cells or hgf. |
2016-04-08 |
2023-08-13 |
Not clear |