| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Giulio Galla, Nadine Praeg, Theresa Rzehak, Else Sprecher, Filippo Colla, Julia Seeber, Paul Illmer, Heidi C Hauff. Comparison of DNA extraction methods on different sample matrices within the same terrestrial ecosystem. Scientific reports. vol 14. issue 1. 2024-04-15. PMID:38622248. |
dna extraction kit was associated with changes in the relative abundance of hundreds of asvs, in the same samples, resulting in significant differences in alpha and beta diversity estimates of their microbiotas. |
2024-04-15 |
2024-04-18 |
Not clear |
| Giulio Galla, Nadine Praeg, Theresa Rzehak, Else Sprecher, Filippo Colla, Julia Seeber, Paul Illmer, Heidi C Hauff. Comparison of DNA extraction methods on different sample matrices within the same terrestrial ecosystem. Scientific reports. vol 14. issue 1. 2024-04-15. PMID:38622248. |
we show that the macherey-nagel nucleospin® soil kit was associated with the highest alpha diversity estimates, providing the highest contribution to the overall sample diversity, as indicated by comparisons with computationally assembled reference communities, and is recommended to be used for any large-scale microbiota study of terrestrial ecosystems. |
2024-04-15 |
2024-04-18 |
Not clear |
| Keita Sasa, Raku Son, Akiko Oguchi, Karin Ashizawa, Nobuhiko Hasegawa, Daisuke Kubota, Yoshiyuki Suehara, Tatsuya Takagi, Taketo Okubo, Keisuke Akaike, Kiichi Sugimoto, Makoto Takahashi, Kazuhiro Sakamoto, Takashi Hashimoto, Shinji Mine, Tetsu Fukunaga, Muneaki Ishijima, Takuo Hayashi, Takashi Yao, Yasuhiro Murakawa, Tsuyoshi Sait. NTRK2 expression in gastrointestinal stromal tumors with a special emphasis on the clinicopathological and prognostic impacts. Scientific reports. vol 14. issue 1. 2024-01-09. PMID:38191907. |
gastrointestinal stromal tumors (gists) are typically characterized by activating mutations of the kit proto-oncogene receptor tyrosine kinase (kit) or platelet-derived growth factor receptor alpha (pdgfra). |
2024-01-09 |
2024-01-10 |
Not clear |
| Georg Greiner, Nadine Witzeneder, Klara Klein, Simone Tangermann, Petra Kodajova, Eva Jaeger, Franz Ratzinger, Marlene C Gerner, Mohamad Jawhar, Sigrid Baumgartner, Karin Fruehwirth, Klaus G Schmetterer, Johannes Zuber, Karoline V Gleixner, Matthias Mayerhofer, Ilse Schwarzinger, Ingrid Simonitsch-Klupp, Harald Esterbauer, Constance Baer, Wencke Walter, Manja Meggendorfer, Robert Strassl, Torsten Haferlach, Karin Hartmann, Lukas Kenner, Wolfgang R Sperr, Andreas Reiter, Veronika Sexl, Michel Arock, Peter Valent, Gregor Hoerman. TNF alpha promotes clonal dominance of KIT D816V+ cells in mastocytosis: role of survivin and impact on prognosis. Blood. 2023-12-24. PMID:38142424. |
tnf alpha promotes clonal dominance of kit d816v+ cells in mastocytosis: role of survivin and impact on prognosis. |
2023-12-24 |
2023-12-27 |
human |
| Lucía Chaves-Blanco, Adolfo de Salazar, Ana Fuentes, Laura Viñuela, Javier Perez-Florido, Joaquín Dopazo, Federico Garcí. Evaluation of a combined detection of SARS-CoV-2 and its variants using real-time allele-specific PCR strategy: an advantage for clinical practice. Epidemiology and infection. vol 151. 2023-12-21. PMID:37997654. |
when the alpha variant was dominant, the kit included the hv69/70 deletion, e and n genes. |
2023-12-21 |
2023-12-23 |
Not clear |
| Michael C Heinrich, Christopher L Corless, George D Demetri, Charles D Blanke, Margaret von Mehren, Heikki Joensuu, Laura S McGreevey, Chang-Jie Chen, Annick D Van den Abbeele, Brian J Druker, Beate Kiese, Burton Eisenberg, Peter J Roberts, Samuel Singer, Christopher D M Fletcher, Sandra Silberman, Sasa Dimitrijevic, Jonathan A Fletche. Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. vol 41. issue 31. 2023-10-30. PMID:37890277. |
most gastrointestinal stromal tumors (gists) express constitutively activated mutant isoforms of kit or kinase platelet-derived growth factor receptor alpha (pdgfra) that are potential therapeutic targets for imatinib mesylate. |
2023-10-30 |
2023-11-08 |
Not clear |
| Asami Arita, Tsuyoshi Takahashi, Kiyokazu Nakajima, Yukinori Kurokawa, Seiichi Hirota, Toshirou Nishida, Kotaro Yamashita, Takuro Saito, Koji Tanaka, Tomoki Makino, Makoto Yamasaki, Kunihiko Kawai, Yuichi Motoyama, Eiichi Morii, Hidetoshi Eguchi, Yuichiro Dok. Surgery for multiple gastric gastrointestinal stromal tumors and large esophageal diverticulum related to germline mutation of the KIT gene: a case report. Surgical case reports. vol 9. issue 1. 2023-10-26. PMID:37870660. |
familial gastrointestinal stromal tumors (gists) are mesenchymal tumors of the digestive tract caused by germline gain-of-function mutations in the kit gene or platelet-derived growth factor receptor alpha gene (pdgfra). |
2023-10-26 |
2023-11-08 |
Not clear |
| Akash Patel, Akash Shah, Ishan Patel, Sunil Pate. Anorectal Gastrointestinal Stromal Tumor: Report of a Rare Case. Cureus. vol 15. issue 5. 2023-06-09. PMID:37292549. |
gists involve the expression of kit (cd117) tyrosine kinase with the presence of mutations in kit or platelet-derived growth factor alpha (pdgfrα) and are identified as an important target in therapy. |
2023-06-09 |
2023-08-14 |
dog |
| Hyunjee V Kwak, Katherine J Tardy, Andrew Allbee, Kristen Stashek, Ronald P DeMatte. Surgical Management of Germline Gastrointestinal Stromal Tumor. Annals of surgical oncology. 2023-04-28. PMID:37115371. |
gastrointestinal stromal tumor (gist) is the most common human sarcoma and usually results from a sporadic mutation in kit or, less frequently, platelet-derived growth factor alpha (pdgfra). |
2023-04-28 |
2023-08-14 |
human |
| Rajshree Verma, Kailash Pati Singh Kushwaha, Neha Chakrawarti, Satya Kumar, Manpreet Kaur, Prince Kumar Gupta, Prabhas Sing. First report of Fusarium incarnatum-equiseti species complex as the causal agent of pod rot of black gram (Vigna mungo L.) in India. Plant disease. 2023-04-27. PMID:37102727. |
for molecular identification of the three isolates, total genomic dna was extracted using the purelink® plant total dna purification kit (invitrogen™, thermofisher scientific, waltham, massachusetts, united states) and used for amplification and sequencing of a portion of the internal transcribed spacer (its) region, the translation elongation factor-1 alpha (ef-1α) gene, and the second largest subunit of rna polymerase (rpb2) gene (white et al. |
2023-04-27 |
2023-08-14 |
Not clear |
| Woong Kee Baek, Pu Ni, Jennifer Zeng, Victoria Collins, Nebras Zeizafou. A Rare Case of Breast Metastatic Gastrointestinal Stromal Tumor. Cureus. vol 15. issue 1. 2023-02-27. PMID:36843793. |
gist is thought to originate from interstitial cell of cajal, and its pathogenesis is related to molecular defects, such as kit receptor tyrosine kinase or platelet-derived growth receptor alpha gene activation. |
2023-02-27 |
2023-08-14 |
Not clear |
| Douglas Wood, Greer Janssen, Imad Aljanab. Extragastrointestinal stromal tumour of the transverse mesocolon mimicking giant ovarian cystic neoplasm. BMJ case reports. vol 16. issue 2. 2023-02-02. PMID:36731947. |
the tumour was found to be kit wild type, with a platelet-derived growth factor receptor alpha d842v mutation identified, conferring intrinsic resistance to imatinib. |
2023-02-02 |
2023-08-14 |
Not clear |
| John A Ligon, R Taylor Sundby, Mary F Wedekind Malone, Fernanda I Arnaldez, Jaydira Del Rivero, Lori Wiener, Ramaprasad Srinivasan, Melissa Spencer, Amanda Carbonell, Haiyan Lei, John Shern, Seth M Steinberg, William D Figg, Cody J Peer, Sara Zimmerman, Josquin Moraly, Xia Xu, Stephen Fox, King Chan, Michael I Barbato, Thorkell Andresson, Naomi Taylor, Karel Pacak, J Keith Killian, Eva Dombi, W Marston Linehan, Markku Miettinen, Richard Piekarz, Lee J Helman, Paul Meltzer, Brigitte Widemann, John Glo. A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-associated Renal Cell Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022-10-27. PMID:36302175. |
succinate dehydrogenase deficient (dsdh) tumors, including pheochromocytoma/paraganglioma, hereditary leiomyomatosis and renal cell cancer-associated renal cell carcinoma (hlrcc-rcc), and gastrointestinal stromal tumors (gists) without kit or platelet derived growth factor receptor alpha mutations are often resistant to cytotoxic chemotherapy, radiotherapy, and many targeted therapies. |
2022-10-27 |
2023-08-14 |
Not clear |
| Zihan Shi, Qiaoyi Kong, Xinghao Li, Wenxin Xu, Chengzhi Mao, Yunfeng Wang, Weibo Song, Jie Huan. The Effects of DNA Extraction Kits and Primers on Prokaryotic and Eukaryotic Microbial Community in Freshwater Sediments. Microorganisms. vol 10. issue 6. 2022-06-24. PMID:35744736. |
our results showed that the fastdna spin kit for soil and dneasy powersoil kit produced much higher dna yield with good reproducibility, and observed more eukaryotic otus compared to the minkagene dna extraction kit, but all three kits exhibited comparable ability in recovering bacterial alpha diversity. |
2022-06-24 |
2023-08-14 |
Not clear |
| Jacqueline Rehner, Georges Pierre Schmartz, Laura Groeger, Jan Dastbaz, Nicole Ludwig, Matthias Hannig, Stefan Rupf, Berthold Seitz, Elias Flockerzi, Tim Berger, Matthias Christian Reichert, Marcin Krawczyk, Eckart Meese, Christian Herr, Robert Bals, Sören L Becker, Andreas Keller, Rolf Mülle. Systematic cross-biospecimen evaluation of DNA extraction kits for long- and short-read multi-metagenomic sequencing studies. Genomics, proteomics & bioinformatics. 2022-06-09. PMID:35680095. |
while profiles of the specimen type showed close proximity to each other, we observed notable differences in the alpha diversity and composition of the microbiota depending on the dna extraction kit. |
2022-06-09 |
2023-08-14 |
Not clear |
| Xuejiao Wang, Song Wang, Ajiao Hou, Huan Yu, Jiaxu Zhang, Senwang Zheng, Shihao Zhang, Jiahao Lv, Jiaojiao Dong, Liu Yang, Hai Jiang, Haixue Kuan. The effect of anti-alcoholic gastric ulcer of before and after vinegar processed Yuanhu Zhitong prescription based on spectral effect relationship. Biomedical chromatography : BMC. 2022-05-16. PMID:35577531. |
the degree of gastric mucosa injury was evaluated by he staining and the contents of malondialdehyde and tumor necrosis factor alpha and superoxide dismutase were detected by elisa kit. |
2022-05-16 |
2023-08-13 |
Not clear |
| A Trullas-Jimeno, J Delgado, B Garcia-Ochoa, I Wang, A Sancho-Lopez, C Payares-Herrera, M L Dalhus, B O Strøm, E J Egeland, H Enzmann, F Pignatt. The EMA assessment of avapritinib in the treatment of gastrointestinal stromal tumours harbouring the PDGFRA D842V mutation. ESMO open. vol 6. issue 3. 2021-10-29. PMID:34023541. |
avapritinib is a protein kinase inhibitor designed to selectively inhibit oncogenic kit and platelet-derived growth factor receptor alpha (pdgfra) mutants by targeting the active conformation of the kinase. |
2021-10-29 |
2023-08-13 |
Not clear |
| Maite Aubry, Iotefa Teiti, Anita Teissier, Vaea Richard, Teheipuaura Mariteragi-Helle, Kiyojiken Chung, Farah Deen, Tuterarii Paoaafaite, Van-Mai Cao-Lormea. Self-collection and pooling of samples as resources-saving strategies for RT-PCR-based SARS-CoV-2 surveillance, the example of travelers in French Polynesia. PloS one. vol 16. issue 9. 2021-09-20. PMID:34473769. |
retrospective testing of positive samples self-collected from october 20th, 2020, using variants-specific amplification kit and spike gene sequencing, found at least 6 residents infected by the alpha variant. |
2021-09-20 |
2023-08-13 |
human |
| Areli Martínez-Gamboa, María Dolores Niembro-Ortega, Pedro Torres-González, Janeth Santiago-Cruz, Nancy Guadalupe Velázquez-Zavala, Andrea Rangel-Cordero, Brenda Crabtree-Ramírez, Armando Gamboa-Domínguez, Edgardo Reyes-Gutiérrez, Gustavo Reyes-Terán, Víctor Hugo Lozano-Fernandez, Víctor Hugo Ahumada-Topete, Pedro Martínez-Ayala, Marisol Manríquez-Reyes, Juan Pablo Ramírez-Hinojosa, Patricia Rodríguez-Zulueta, Christian Hernández-León, Jesús Ruíz-Quiñones, Norma Eréndira Rivera-Martínez, Alberto Chaparro-Sánchez, Jaime Andrade-Villanueva, Luz Alicia González-Hernández, Sofia Cruz-Martínez, Oscar Flores-Barrientos, Jesús Enrique Gaytán-Martínez, Martín Magaña-Aquino, Axel Cervantes-Sánchez, Antonio Olivas-Martínez, Javier Araujo-Meléndez, María Del Rocío Reyes-Montes, Esperanza Duarte-Escalante, María Guadalupe Frías-De León, José Antonio Ramírez, María Lucia Taylor, Alfredo Ponce de León-Garduño, José Sifuentes-Osorni. Diagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico. PLoS neglected tropical diseases. vol 15. issue 3. 2021-06-24. PMID:33684128. |
therefore, the purpose of this multicenter, prospective, double-blinded study done in ten mexican hospitals was to determine the diagnostic accuracy of detecting histoplasma capsulatum antigen in urine using the immy alpha histoplasma eia kit (iahe), clarus histoplasma gm enzyme immunoassay (chgei immy) and miravista histoplasma urine antigen lfa (mvhualfa); as well as the hcp100 and 1281-1283220scar nested pcrs in blood, bone-marrow, tissue biopsies and urine. |
2021-06-24 |
2023-08-13 |
Not clear |
| Yue Zhao, Fei Feng, Qing-Hong Guo, Yu-Ping Wang, Rui Zha. Role of succinate dehydrogenase deficiency and oncometabolites in gastrointestinal stromal tumors. World journal of gastroenterology. vol 26. issue 34. 2021-05-14. PMID:32982110. |
approximately 85% of gists are caused by gain-of-function mutations in the tyrosine kinase receptor kit or platelet-derived growth factor receptor alpha (pdgfra). |
2021-05-14 |
2023-08-13 |
human |