| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yunxian Dong, Youliang Zhang, Fangwei Li, Bing Tang, Dongming Lv, Haibin Wang, Shengkang Lu. GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing. Journal of leukocyte biology. vol 115. issue 5. 2024-04-29. PMID:37774495. |
in vitro, ros levels and nox4 expression were increased after hg treatment of adscs, while the oxidative stress marker malondialdehyde was increased; mitochondrial membrane potential was decreased; inflammatory aging-related indicators such as p16, p21, matrix metalloproteinase-1 (mmp1), mmp3, interleukin-6, and β-galactosidase were increased; and migration was weakened. |
2024-04-29 |
2024-05-02 |
mouse |
| Jie Zhou, Chau Q Le, Yun Zhang, James A Well. A general approach for selection of epitope-directed binders to proteins. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 19. 2024-04-29. PMID:38683990. |
we generated antibodies that recognize the junction between the pro- and catalytic domains for three different matrix metalloproteases (mmps), mmp1, mmp3, and mmp9, that selectively block activation of each of these enzymes and impair cell migration. |
2024-04-29 |
2024-05-03 |
Not clear |
| Mohammad S El-Wetidy, Mohamad I Rady, Islam Rady, Hamed Hela. Urolithin A affects cellular migration and modulates matrix metalloproteinase expression in colorectal cancer cells. Cell biochemistry and function. vol 42. issue 3. 2024-04-16. PMID:38622949. |
the western blot analysis investigation revealed that ua inhibits cellular metastasis by lowering the expression levels of matrix metalloproteinases 1 and 2 (mmp1 and mmp2) by more than 43% and 41% (p < .001) in ht29, 28% and 149% (p < .001) in sw480, and 90% and 74% (p < .001) in sw620, respectively, at a 100 µm dosage of ua compared to the control. |
2024-04-16 |
2024-04-18 |
Not clear |
| Rui Lin, Yuexin Zhu, Weiyao Chen, Zhiao Wang, Yuan Wang, Jie D. Identification of Circulating Inflammatory Proteins Associated with Calcific Aortic Valve Stenosis by Multiplex Analysis. Cardiovascular toxicology. 2024-04-08. PMID:38589550. |
mendelian randomization showed that elevated levels of two proteins, namely, matrix metallopeptidase-1 (mmp1) and sirtuin 2 (sirt2), were associated with an increased risk of cavs. |
2024-04-08 |
2024-04-11 |
Not clear |
| Ruihui Yang, Huainian Zhang, Zexin Chen, Tao Zhang, Peng Wei, Huaguo Liang, Yaoyao He, Changtao Zheng, Xicheng Wang, Yongli Zhan. Drug resistance‑related gene targets and molecular mechanisms in the A2780/Taxol‑resistant epithelial ovarian cancer cell line. Oncology letters. vol 27. issue 5. 2024-04-08. PMID:38586210. |
further bioinformatics analysis revealed that matrix metalloproteinase 1 (mmp1), zyxin (zyx) and unc-5 netrin receptor c (unc5c) may be gene targets related to paclitaxel resistance. |
2024-04-08 |
2024-04-10 |
Not clear |
| Yat-Yin Law, Hsiang-Lin Lee, Chu-Liang Lin, Pei-Ni Chen, Pei-Han Wang, Yi-Hsien Hsieh, Chien-Min Che. Asiatic acid inhibits osteosarcoma cell migration and invasion via the AKT/Sp1/MMP1 axis. Environmental toxicology. 2024-04-03. PMID:38567545. |
aa suppressed osteosarcoma cell migration and invasion by down-regulating matrix metalloproteinase 1 (mmp1) expression. |
2024-04-03 |
2024-04-05 |
human |
| Chunfang Xi, Zhendi Song, Qingyu Cui, Ye Zhao, Kaifu Li, Hua Kan. Elevated MMP1 Expression in Carcinoma-Associated Fibroblasts of Breast Cancer Contributes to Tumor Progression and Unfavorable Prognosis. Annals of clinical and laboratory science. vol 54. issue 1. 2024-03-21. PMID:38514057. |
several studies reported upregulated matrix metallopeptidase 1 (mmp1) expression in various cancers. |
2024-03-21 |
2024-03-24 |
Not clear |
| Meiling Liu, Shaokai Huang, Sunmin Par. Inhibitory effects of bioactive compounds on UVB-induced photodamage in human keratinocytes: modulation of MMP1 and Wnt signaling pathways. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 2024-02-07. PMID:38326693. |
using in silico analysis, we chose compounds to reduce binding energy with matrix metalloproteinase-1 (mmp1). |
2024-02-07 |
2024-02-10 |
human |
| Yu Chen, Li Huang, Rui-Huan Gan, Shuo Yuan, Ting Lan, Dali Zheng, You-Guang L. IL-8 activates fibroblasts to promote the invasion of HNSCC cells via STAT3-MMP1. Cell death discovery. vol 10. issue 1. 2024-02-06. PMID:38320998. |
matrix metalloproteinase-1 (mmp1) has an aberrant expression relevant to various behaviors of cancers. |
2024-02-06 |
2024-02-09 |
Not clear |
| Yu Chen, Li Huang, Rui-Huan Gan, Shuo Yuan, Ting Lan, Dali Zheng, You-Guang L. IL-8 activates fibroblasts to promote the invasion of HNSCC cells via STAT3-MMP1. Cell death discovery. vol 10. issue 1. 2024-02-06. PMID:38320998. |
as dominant components of the tumor stroma, fibroblasts constitute an important source of matrix metalloproteinase (mmps) including mainly mmp1. |
2024-02-06 |
2024-02-09 |
Not clear |
| Yu Xiao, Jieqi Qian, Xiaohui Deng, Huifeng Zhang, Jiancheng Wang, Zhijun Luo, Lingyan Zh. Macrophages regulate healing-associated fibroblasts in diabetic wound. Molecular biology reports. vol 51. issue 1. 2024-01-25. PMID:38270651. |
recently, a fibroblast subpopulation that expresses high matrix metalloproteinase 1 (mmp1), mmp3, mmp11 and chitinase-3-like protein 1 (chi3l1) was associated with a successful diabetic wound healing. |
2024-01-25 |
2024-01-27 |
Not clear |
| Ji-Yong Jung, Joong Hyun Shim, Su Hae Cho, Il-Hong Bae, Seung Ha Yang, Jinsick Kim, Hye Won Lim, Dong Wook Shi. The Anti-Diabetic Pinitol Improves Damaged Fibroblasts. Biomolecules & therapeutics. 2024-01-04. PMID:38173141. |
we also found that pinitol significantly antagonized the uva-induced up-regulation of matrix metalloproteinase 1 (mmp1), and the uva-induced down-regulation of collagen type i and tissue inhibitor of metalloproteinases 1 (timp1) in hdes. |
2024-01-04 |
2024-01-06 |
human |
| Qing Ruan, Cuijie Wang, Yunfeng Zhang, Jiayang Su. Ruscogenin attenuates cartilage destruction in osteoarthritis through suppressing chondrocyte ferroptosis via Nrf2/SLC7A11/GPX4 signaling pathway. Chemico-biological interactions. 2023-12-20. PMID:38122922. |
in vitro, il-1β-induced inflammation and degradation of extracellular matrix were inhibited by rus, as confirmed by the inhibition of pge2, no, mmp1, and mmp3 by rus. |
2023-12-20 |
2023-12-23 |
mouse |
| Yuchen Ge, Man Li, Shirui Bai, Cui Chen, Shulin Zhang, Jiamao Cheng, Xiaobo Wan. Doxercalciferol alleviates UVB-induced HaCaT cell senescence and skin photoaging. International immunopharmacology. vol 127. 2023-12-17. PMID:38104366. |
then, we found that the senescence β-galactosidase (sa-β-gal) positive rate, senescence-related protein (p16), aging-related genes (p21 and p53), senescence-associated secretory phenotype (sasp), inflammatory driving factors (il-1β and il-6) and matrix metalloproteinases (mmps) (mmp1 and mmp9) were upregulated in hacat cells after uvb irradiation. |
2023-12-17 |
2023-12-21 |
mouse |
| Zheng Zhao, Liang Li, Ruichen Zeng, Liangguan Lin, Dongwei Yuan, Yejie Wen, Na Li, Yingying Cui, Shiming Zhu, Zhi-Min Zhang, Sheng Li, Chonghua Re. 5mC modification orchestrates choriogenesis and fertilization by preventing prolonged ftz-f1 expression. Nature communications. vol 14. issue 1. 2023-12-12. PMID:38086980. |
the hypomethylation at the ftz-f1 promoter region increases and prolongs ftz-f1 expression in ovarian follicle cells during choriogenesis, which consequently causes aberrantly high levels of 20-hydroxyecdysone and excessively upregulates the extracellular matrix remodeling gene mmp1. |
2023-12-12 |
2023-12-17 |
Not clear |
| Mi Hee Kwack, Ons Ben Hamida, Min Kyu Kim, Moon Kyu Kim, Young Kwan Sun. Establishment and characterization of matched immortalized human frontal and occipital scalp dermal papilla cell lines from androgenetic alopecia. Scientific reports. vol 13. issue 1. 2023-12-04. PMID:38049592. |
furthermore, when the cells were cultured in a 3d environment mimicking in vivo conditions, the 3d cultured frontal dp cell line exhibited weaker sphere aggregation than the occipital dp cell line due to the increased expression of matrix metalloproteinase 1 (mmp1), mmp3, and mmp9. |
2023-12-04 |
2023-12-10 |
human |
| Yizhen Sima, Junwei Li, Leimei Xu, Chengzhen Xiao, Lisha Li, Ling Wang, Yisong Che. Quercetin antagonized advanced glycated end products induced apoptosis and functional inhibition of fibroblasts from the prolapsed uterosacral ligament. Drug discoveries & therapeutics. 2023-12-03. PMID:38044121. |
quercetin reduced the gene expressions of lysyl oxidase like protein 1 (loxl1)and matrix metallopeptidase 1 (mmp1), and increased the gene expressions of lysyl oxidase (lox) and fibrillin 2 (fbn2) in fibroblasts. |
2023-12-03 |
2023-12-10 |
Not clear |
| Szymon W Mank. Mapping the Binding Sites of MMPs on Types II and III Collagens Using Triple-Helical Peptide Toolkits. Methods in molecular biology (Clifton, N.J.). vol 2747. 2023-12-01. PMID:38038933. |
here i describe a simple solid-phase binding assay utilizing a biotin-streptavidin system to screen the collagen toolkits for binding of two distinct matrix metalloproteinases (mmps) implicated in cancer: the collagenolytic mmp1 (collagenase 1) and the non-collagenolytic mmp3 (stromelysin 1). |
2023-12-01 |
2023-12-10 |
Not clear |
| Runxiao Lv, Lili Du, Lunhao Ba. RNF125, transcriptionally regulated by NFATC2, alleviates osteoarthritis via inhibiting the Wnt/β-catenin signaling pathway through degrading TRIM14. International immunopharmacology. vol 125. issue Pt B. 2023-11-11. PMID:37951197. |
our results defined that adenovirus-mediated overexpression of rnf125 inhibited the degradation of extracellular matrix of chondrocytes induced by il-1β, as revealed by increased chondrocyte viability, upregulated col2a1 and acan levels, and downregulated mmp1, mmp13 and adamts5 levels, which was abrogated by nr4a2 knockdown. |
2023-11-11 |
2023-11-20 |
rat |
| Ruicai Gu, Tae-Dong Kim, Hoogeun Song, Yuan Sui, Sook Shin, Sangphil Oh, Ralf Janknech. SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A. JCI insight. vol 8. issue 20. 2023-10-23. PMID:37870957. |
joint mutation of these lysine residues suppressed jmjd2a's ability to stimulate the mmp1 matrix metallopeptidase promoter upon recruitment by the etv1 transcription factor. |
2023-10-23 |
2023-11-08 |
Not clear |