| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Beata Lecka-Czernik, Mohd Parvez Khan, Joshua Letson, Sudipta Baroi, Amit Chougul. Regulatory Effect of Osteocytes on Extramedullary and Bone Marrow Adipose Tissue Development and Function. Current osteoporosis reports. 2024-04-16. PMID:38625510. |
this review summarizes evidence on osteocyte support of extramedullary and bone marrow adipocyte development and discusses the role of endogenous osteocyte activities of nuclear receptors peroxisome proliferator-activated receptor gamma (pparg) and alpha (ppara) in this support. |
2024-04-16 |
2024-04-18 |
Not clear |
| Yanping Li, Feng Yang, Wanying Lang, Qi An, Zhi Pan, Wenyu Shi, Xiaowei Sh. Network pharmacology and pharmacological evaluation of Wenzheng Jiedu Powder Modified Formula for neuropathic pain relief. General physiology and biophysics. vol 43. issue 2. 2024-03-13. PMID:38477604. |
wjpmf significantly improved pain behaviors in sni rats by regulating atp-binding cassette transporter a1 (abca1), peroxisome proliferator-activated receptor alpha (ppara), peroxisome proliferator-activated receptor gamma (pparg), and superoxide dismutase 2 (sod2) expression, which were key targets involved in the peroxisome proliferator-activated receptor (ppar) signaling pathway. |
2024-03-13 |
2024-03-15 |
rat |
| Vladimir Khavinson, Natalia Linkova, Ekaterina Kozhevnikova, Svetlana Trofimov. EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease. Molecules (Basel, Switzerland). vol 26. issue 1. 2021-04-13. PMID:33396470. |
thus, the edr peptide can change the activity of the mapk/erk signaling pathway, the synthesis of proapoptotic proteins (caspase-3, p53), proteins of the antioxidant system (sod2, gpx1), transcription factors ppara, pparg, serotonin, calmodulin. |
2021-04-13 |
2023-08-13 |
mouse |
| Agnieszka Blitek, Magdalena Szymansk. Regulation of expression and role of peroxisome proliferator-activated receptors (PPARs) in luminal epithelial and stromal cells of the porcine endometrium. Theriogenology. vol 127. 2019-02-21. PMID:30677596. |
in the present study, cultured luminal epithelial (le) and stromal (st) cells of the porcine endometrium were used to examine (1) the effect of conceptus exposed medium (cem) on mrna and protein expression and dna binding activity of ppara, ppard, and pparg isoforms, and (2) the effect of ppara, ppard, and pparg agonists on the expression of selected genes, apoptosis, and cell proliferation. |
2019-02-21 |
2023-08-13 |
Not clear |
| Reza Salehi, Divakar J Ambros. Prepartum maternal diets supplemented with oilseeds alter the fatty acid profile in bovine neonatal plasma possibly through reduced placental expression of fatty acid transporter protein 4 and fatty acid translocase. Reproduction, fertility, and development. vol 29. issue 9. 2018-07-23. PMID:27938626. |
feeding of la versus ola prepartum tended to increase peroxisome proliferator-activated receptor α (ppara) expression, whereas peroxisome proliferator-activated receptor δ (ppard) and peroxisome proliferator-activated receptor γ (pparg) expression tended to be higher in ola- than la-fed cows. |
2018-07-23 |
2023-08-13 |
cattle |
| R W Schwenk, W Jonas, S B Ernst, A Kammel, M Jähnert, A Schürman. Diet-dependent alterations of hepatic Scd1 expression are accompanied by differences in promoter methylation. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 45. issue 11. 2014-06-05. PMID:23803969. |
in contrast, expression of transcription factors peroxisome proliferator activated receptor alpha and gamma (ppara, pparg), and sterol regulatory element binding transcription factor 1 (srebf1) was not affected. |
2014-06-05 |
2023-08-12 |
mouse |
| E Dervishi, C Serrano, M Joy, M Serrano, C Rodellar, J H Calv. The effect of feeding system in the expression of genes related with fat metabolism in semitendinous muscle in sheep. Meat science. vol 89. issue 1. 2011-09-12. PMID:21543161. |
the effect of feeding system on the expression of lpl, acaca, fasn, fabp4, dgat1, scd, cpt1b, prkaa2, lep, srebp1, pparg, ppara and cebpb genes in semitendinous muscle was studied. |
2011-09-12 |
2023-08-12 |
Not clear |
| Ignacio Fernández, Maria Darias, Karl B Andree, David Mazurais, Jose Luís Zambonino-Infante, Enric Gisber. Coordinated gene expression during gilthead sea bream skeletogenesis and its disruption by nutritional hypervitaminosis A. BMC developmental biology. vol 11. 2011-07-22. PMID:21306609. |
therefore, in order to gain further knowledge of fish larval development and its disruption by nutritional va imbalance, the relative expression of some rars and rxrs, as well as several genes involved in morpho- and skeletogenesis such as peroxisome proliferator-activated receptors (ppara, pparb and pparg); retinol-binding protein (rbp); insulin-like growth factors i and ii (igf1 and igf2, respectively); bone morphogenetic protein 2 (bmp2); transforming growth factor β-1 (tgfb1); and genes encoding different extracellular matrix (ecm) proteins such as matrix gla protein (mgp), osteocalcin (bglap), osteopontin (spp1), secreted protein acidic and rich in cysteine (sparc) and type i collagen α1 chain (col1a1) have been studied in gilthead sea bream. |
2011-07-22 |
2023-08-12 |
Not clear |
| M C Ryan, P V Desmond, J L Slavin, M Congi. Expression of genes involved in lipogenesis is not increased in patients with HCV genotype 3 in human liver. Journal of viral hepatitis. vol 18. issue 1. 2011-03-22. PMID:20196803. |
we measured by real-time pcr the expression of genes involved in lipid metabolism [acetyl-coenzyme a carboxylase alpha, apolipoprotein b (apob), diacylglycerol o-acyltransferase 2, fatty acid-binding protein 1, fatty acid synthase, microsomal triglyceride transfer protein (mttp), peroxisome proliferator-activated receptor alpha (ppara), peroxisome proliferator-activated receptor gamma (pparg), protein kinase amp-activated alpha 1 catalytic subunit (prkaa1) and sterol regulatory element-binding transcription factor 1 (srebf1)] in liver biopsies from patients infected with hcv genotype-1 (hcvgt1), hcvgt3 and hepatitis b (hbv) using β-glucuronidase (gusb) and splicing factor arginine/serine-rich 4 (sfrs4) as housekeeping genes. |
2011-03-22 |
2023-08-12 |
human |
| Alessandra Bitto, Domenica Altavilla, Antonio Bonaiuto, Francesca Polito, Letteria Minutoli, Vincenzo Di Stefano, Daniela Giuliani, Salvatore Guarini, Vincenzo Arcoraci, Francesco Squadrit. Effects of aglycone genistein in a rat experimental model of postmenopausal metabolic syndrome. The Journal of endocrinology. vol 200. issue 3. 2009-07-23. PMID:19066292. |
genistein treatment decreased sbp and plasma lipids, ameliorated endothelial dysfunction and insulin resistance, increased hdl cholesterol, and enhanced liver expression of ppara and pparg. |
2009-07-23 |
2023-08-12 |
rat |
| Alessandra Bitto, Domenica Altavilla, Antonio Bonaiuto, Francesca Polito, Letteria Minutoli, Vincenzo Di Stefano, Daniela Giuliani, Salvatore Guarini, Vincenzo Arcoraci, Francesco Squadrit. Effects of aglycone genistein in a rat experimental model of postmenopausal metabolic syndrome. The Journal of endocrinology. vol 200. issue 3. 2009-07-23. PMID:19066292. |
liver expression of the peroxisome proliferator-activated receptor alpha (ppara and gamma (pparg was also assessed. |
2009-07-23 |
2023-08-12 |
rat |
| Luisa Klotz, Stephan Schmidt, Reinhard Heun, Thomas Klockgether, Heike Kölsc. Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis. Neuroscience letters. vol 449. issue 1. 2009-04-15. PMID:18977277. |
we investigated the association of two common single nucleotide polymorphisms in the ppara (leu162val) and the pparg (pro12ala) genes in 116 patients with clinically definite multiple sclerosis (ms) and 211 age-matched healthy controls. |
2009-04-15 |
2023-08-12 |
Not clear |
| Johanna Samulin, Ingunn Berget, Sigbjørn Lien, Hilde Sundvol. Differential gene expression of fatty acid binding proteins during porcine adipogenesis. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 151. issue 2. 2008-11-17. PMID:18621139. |
in this study we demonstrate that fabp3, fabp4 and fabp5 expression is correlated with that of the peroxisome proliferator-activated receptors alpha and gamma (ppara and pparg). |
2008-11-17 |
2023-08-12 |
Not clear |
| I I Akhmetov, D V Popov, I A Mozhaĭskaia, S S Missina, I V Astratenkova, O L Vinogradova, V A Rogozki. [Association of regulatory genes polymorphisms with aerobic and anaerobic performance of athletes]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 93. issue 8. 2007-11-09. PMID:17926914. |
thus, ppara g, pparg ala, ppard c and pgcia gly alleles can be considered as genetic markers associated with enhanced physical performance. |
2007-11-09 |
2023-08-12 |
Not clear |
| B Kieć-Wilk, A Dembińska-Kieć, A Olszanecka, M Bodzioch, K Kawecka-Jaszc. The selected pathophysiological aspects of PPARs activation. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 56. issue 2. 2005-08-25. PMID:15985699. |
in hypertension-induced cardiac hypertrophy, both ppara and pparg activation reveal cardio-protective effect. |
2005-08-25 |
2023-08-12 |
Not clear |
| J Skogsberg, K Kannisto, L Roshani, E Gagne, A Hamsten, C Larsson, E Ehrenbor. Characterization of the human peroxisome proliferator activated receptor delta gene and its expression. International journal of molecular medicine. vol 6. issue 1. 2000-08-21. PMID:10851270. |
three different ppars; alpha (ppara), gamma (pparg) and delta (ppard) have been characterized and they are distinguished from each other by tissue distribution and cell activation. |
2000-08-21 |
2023-08-12 |
human |