| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zihao Li, Cun-Jin Zhan. Isolation and Culture of Mouse Primary Microglia and Oligodendrocyte Precursor Cells. Methods in molecular biology (Clifton, N.J.). vol 2782. 2024-04-15. PMID:38622401. |
microglia and oligodendrocyte precursor cells (opcs) are critical glia subsets in the central nervous system (cns) and are actively engaged in a body of diseases, such as stroke, alzheimer's disease, multiple sclerosis, etc. |
2024-04-15 |
2024-04-18 |
mouse |
| Zuzana Amlerova, Martina Chmelova, Miroslava Anderova, Lydia Vargov. Reactive gliosis in traumatic brain injury: a comprehensive review. Frontiers in cellular neuroscience. vol 18. 2024-03-14. PMID:38481632. |
various glial cell types participate in the scar formation, but this process is mostly attributed to reactive astrocytes and microglia, which play important roles in several brain pathologies. |
2024-03-14 |
2024-03-16 |
Not clear |
| Changran Niu, Xinpei Yue, Juan Ji An, Robert Bass, Haifei Xu, Baoji X. Genetic Dissection of BDNF and TrkB Expression in Glial Cells. Biomolecules. vol 14. issue 1. 2024-01-23. PMID:38254691. |
we performed immunohistochemistry with glial cell markers to examine the expression of bdnf and trkb in microglia, astrocytes, and oligodendrocytes. |
2024-01-23 |
2024-01-25 |
mouse |
| Michael Morales, Anna P Findley, Diana M Mitchel. Intercellular contact and cargo transfer between Müller glia and to microglia precede apoptotic cell clearance in the developing retina. Development (Cambridge, England). vol 151. issue 1. 2024-01-04. PMID:38174987. |
intercellular contact and cargo transfer between müller glia and to microglia precede apoptotic cell clearance in the developing retina. |
2024-01-04 |
2024-01-06 |
zebrafish |
| Michael Morales, Anna P Findley, Diana M Mitchel. Intercellular contact and cargo transfer between Müller glia and to microglia precede apoptotic cell clearance in the developing retina. Development (Cambridge, England). vol 151. issue 1. 2024-01-04. PMID:38174987. |
müller glia actively engage with dying cells through initial target cell contact and phagocytic cup formation, after which an exchange of the dying cell from müller glia to microglia often takes place. |
2024-01-04 |
2024-01-06 |
zebrafish |
| Shiyu Liang, Jing Zhou, Xiaolin Yu, Shuai Lu, Ruitian Li. Neuronal conversion from glia to replenish the lost neurons. Neural regeneration research. vol 19. issue 7. 2023-12-05. PMID:38051886. |
thus far, many strategies to transform astrocytes, fibroblasts, microglia, müller glia, ng2 cells, and other glial cells to mature and functional neurons, or for the conversion between neuronal subtypes have been developed through the regulation of transcription factors, polypyrimidine tract binding protein 1 (ptbp1), and small chemical molecules or are based on a combination of several factors and the location in the central nervous system. |
2023-12-05 |
2023-12-10 |
Not clear |
| Xiang Cheng, Yanan Geng, Yaqun Jiang, Tong Zhao, Lingling Zhu, Yulin Den. [Characterization and identification of primarily cultured astrocytes and microglia]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 39. issue 10. 2023-10-26. PMID:37877402. |
cell growth results showed that the mixed glia cells of p0 and p1 generation had the best proliferative activity; 97.3% of the high purity microglia could be obtained by mechanical shaking at 170 r/min for 30 min, and there was no significant difference in the morphology of ionized calcium-binding adapter molecule 1 (iba-1) positive microglia and the proportion of m1 and m2 phenotype among the p0, p1 and p2 generations of microglia isolated by the above methods. |
2023-10-26 |
2023-11-08 |
mouse |
| Michael Morales, Anna P Findley, Diana M Mitchel. Intercellular contact and cargo transfer between Müller glia and to microglia precede apoptotic cell clearance in the developing retina. bioRxiv : the preprint server for biology. 2023-10-24. PMID:37873206. |
intercellular contact and cargo transfer between müller glia and to microglia precede apoptotic cell clearance in the developing retina. |
2023-10-24 |
2023-11-08 |
zebrafish |
| Michael Morales, Anna P Findley, Diana M Mitchel. Intercellular contact and cargo transfer between Müller glia and to microglia precede apoptotic cell clearance in the developing retina. bioRxiv : the preprint server for biology. 2023-10-24. PMID:37873206. |
müller glia (mg) actively engage with dying cells through initial target cell contact and phagocytic cup formation after which an exchange of the dying cell from mg to microglia often takes place. |
2023-10-24 |
2023-11-08 |
zebrafish |
| Angela Gomez-Arboledas, Helene Eliane Hirbe. Editorial: Expert opinions on the relationship between microglia, glia, and Alzheimer's disease: 2022. Frontiers in aging neuroscience. vol 15. 2023-09-29. PMID:37771521. |
editorial: expert opinions on the relationship between microglia, glia, and alzheimer's disease: 2022. |
2023-09-29 |
2023-10-07 |
Not clear |
| Changran Niu, Xinpei Yue, Juan Ji An, Haifei Xu, Baoji X. Genetic dissection of BDNF and TrkB expression in glial cells. bioRxiv : the preprint server for biology. 2023-07-28. PMID:37503044. |
we performed immunohistochemistry with glial cell markers to examine the expression of bdnf and trkb in microglia, astrocytes, and oligodendrocytes. |
2023-07-28 |
2023-08-14 |
mouse |
| Amanda Moya-Gómez, Lena Pérez Font, Andreea Burlacu, Yeranddy A Alpizar, Miriam Marañón Cardonne, Bert Brône, Annelies Bronckaer. Extremely Low-Frequency Electromagnetic Stimulation (ELF-EMS) Improves Neurological Outcome and Reduces Microglial Reactivity in a Rodent Model of Global Transient Stroke. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446295. |
it also improved neuronal survival and decreased glia reactivity in the hippocampus, with microglia showing the first signs of treatment effect. |
2023-07-14 |
2023-08-14 |
Not clear |
| Evangelia Xingi, Paraskevi N Koutsoudaki, Irini Thanou, Minh-Son Phan, Maria Margariti, Anja Scheller, Jean-Yves Tinevez, Frank Kirchhoff, Dimitra Thomaido. LPS-Induced Systemic Inflammation Affects the Dynamic Interactions of Astrocytes and Microglia with the Vasculature of the Mouse Brain Cortex. Cells. vol 12. issue 10. 2023-07-06. PMID:37408252. |
the neurovascular unit (nvu), composed of glia (astrocytes, oligodendrocytes, microglia), neurons, pericytes and endothelial cells, is a dynamic interface ensuring the physiological functioning of the central nervous system (cns), which gets affected and contributes to the pathology of several neurodegenerative diseases. |
2023-07-06 |
2023-08-14 |
mouse |
| Heithem M El-Hodiri, James Bentley, Alana Reske, Isabella Palazzo, Warren A Campbell, Nicklaus R Halloy, Andy J Fische. Formation of Müller glia-derived progenitor cells in retinas depleted of microglia. bioRxiv : the preprint server for biology. 2023-06-19. PMID:37333380. |
we generated scrna-seq libraries to identify transcriptional changes in müller glia (mg) that result from the depletion of microglia from the chick retina. |
2023-06-19 |
2023-08-14 |
mouse |
| Peiyao Mao, Yinchen Shen, Xiying Mao, Kun Liu, Jiawei Zhon. The single-cell landscape of alternative transcription start sites of diabetic retina. Experimental eye research. 2023-05-26. PMID:37236522. |
furthermore, by comparing tss expression between healthy and diabetic retina, we identified elevated apoptosis signal in müller glia and microglia, which can be served as a putative early sign of diabetic retinopathy. |
2023-05-26 |
2023-08-14 |
Not clear |
| Dolly Ann Padovani-Claudio, Carla J Ramos, Megan E Capozzi, John S Pen. Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis. Progress in retinal and eye research. vol 94. 2023-04-07. PMID:37028118. |
in vitro stimulation of glia with glucose, angiotensin ii and palmitic acid suggests that: 1) astrocytes may be more responsive than other glia to these products of systemic dyshomeostasis; 2) the effects of hyperglycemia on glia are likely to be largely osmotic; 3) fatty acid accumulation may compound dr pathophysiology by promoting predominantly proinflammatory and proangiogenic transcriptional alterations of macro and microglia; and 4) cell-targeted therapies may offer safer and more effective avenues for dr treatment as they may circumvent the complication of pleiotropism in retinal cell responses. |
2023-04-07 |
2023-08-14 |
Not clear |
| Yemmy Soler, Myosotys Rodriguez, Dana Austin, Cyrille Gineste, Cohava Gelber, Nazira El-Hag. SERPIN-Derived Small Peptide (SP16) as a Potential Therapeutic Agent against HIV-Induced Inflammatory Molecules and Viral Replication in Cells of the Central Nervous System. Cells. vol 12. issue 4. 2023-02-25. PMID:36831299. |
despite the success of combined antiretroviral therapy (cart) increasing the survival rate in human immunodeficiency virus (hiv) patients, low levels of viremia persist in the brain of patients leading to glia (microglia and astrocytes)-induced neuroinflammation and consequently, the reactivation of hiv and neuronal injury. |
2023-02-25 |
2023-08-14 |
mouse |
| Yong Chen, Dan Li, Ningcen Li, PeiYong Loh, Yi Guo, Xiyou Hu, Jingyu Zhang, Baomin Dou, Lifen Wang, Chaobo Yang, Tao Guo, Shuangli Chen, Zhen Liu, Bo Chen, Zelin Che. Role of nerve signal transduction and neuroimmune crosstalk in mediating the analgesic effects of acupuncture for neuropathic pain. Frontiers in neurology. vol 14. 2023-02-09. PMID:36756246. |
moreover, neuroinflammation in pain can be inhibited by acupuncture through inhibiting jak2/stat3, pi3k/mtor pathways, down regulating chemokine receptor cx3cr1 on microglia and up regulating adenosine receptor a1rs on astrocytes, inhibiting the activation of glia and reducing tnf-α and other inflammatory substances. |
2023-02-09 |
2023-08-14 |
Not clear |
| Melissa K Edler, Emily L Munger, Hannah Maycon, William D Hopkins, Patrick R Hof, Chet C Sherwood, Mary Ann Raghant. The association of astrogliosis and microglial activation with aging and Alzheimer's disease pathology in the chimpanzee brain. Journal of neuroscience research. 2023-01-17. PMID:36647571. |
vascular amyloid correlated with decreased astrocyte and microglia densities, while tau lesions were associated with morphological changes in microglia and greater total glia density and glia: neuron ratio. |
2023-01-17 |
2023-08-14 |
human |
| Fatme Seval Ismail, Pedro M Faustmann, Marie-Luise Kümmel, Eckart Förster, Timo Jendrik Faustmann, Franco Corvac. Brivaracetam exhibits mild pro-inflammatory features in an Frontiers in cellular neuroscience. vol 16. 2022-11-21. PMID:36406753. |
primary rat astrocytes co-cultures containing 5%-10% (m5, "physiological" conditions) or 30%-40% (m30, "pathological inflammatory" conditions) of microglia were treated with different concentrations of brv (0.5, 2, 10, and 20 μg/ml) for 24 h. glial cell viability was measured by mtt assay. |
2022-11-21 |
2023-08-14 |
rat |