| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zihao Li, Cun-Jin Zhan. Isolation and Culture of Mouse Primary Microglia and Oligodendrocyte Precursor Cells. Methods in molecular biology (Clifton, N.J.). vol 2782. 2024-04-15. PMID:38622401. |
microglia and oligodendrocyte precursor cells (opcs) are critical glia subsets in the central nervous system (cns) and are actively engaged in a body of diseases, such as stroke, alzheimer's disease, multiple sclerosis, etc. |
2024-04-15 |
2024-04-18 |
mouse |
| Pegah Haghighi, Mandee K Schaub, Adam H Shebindu, Gayathri Vijayakumar, Armaan Sood, Rafael Granja-Vazquez, Sourav S Patnaik, Caroline N Jones, Gregory O Dussor, Joseph J Pancrazi. In Vitro Pharmacological Modulation of PIEZO1 Channels in Frontal Cortex Neuronal Networks. Brain sciences. vol 14. issue 3. 2024-03-28. PMID:38539612. |
piezo1 has been implicated in astrocyte, microglia, capillary, and oligodendrocyte signaling in the mammalian cortex. |
2024-03-28 |
2024-03-30 |
Not clear |
| Weizhuo Lu, Jiyue We. Crosstalk Among Glial Cells in the Blood-Brain Barrier Injury After Ischemic Stroke. Molecular neurobiology. 2024-01-26. PMID:38279077. |
specifically, we provided an updated overview of phenotypic transformation of microglia and astrocytes, as well as uncovered the crosstalk among astrocyte, microglia, and oligodendrocyte in the bbb disruption following ischemic stroke. |
2024-01-26 |
2024-01-29 |
Not clear |
| Santosh Kumar Samal, Madhav Sharma, Jayasri Das Sarm. Isolation and Enrichment of Major Primary Neuroglial Cells from Neonatal Mouse Brain. Bio-protocol. vol 14. issue 2. 2024-01-25. PMID:38268978. |
our current protocol overcomes these drawbacks by utilizing the brain from day-0 pups to isolate cns resident neuroglial cells including astrocytes, microglia, oligodendrocytes [oligodendrocyte precursor cells (opcs) and differentiated oligodendrocytes], and meningeal fibroblasts, as well as hippocampal neurons, avoiding sacrificing pregnant mice, which makes this procedure efficient and cost effective. |
2024-01-25 |
2024-01-27 |
mouse |
| Araks Martirosyan, Rizwan Ansari, Francisco Pestana, Katja Hebestreit, Hayk Gasparyan, Razmik Aleksanyan, Silvia Hnatova, Suresh Poovathingal, Catherine Marneffe, Dietmar R Thal, Andrew Kottick, Victor J Hanson-Smith, Sebastian Guelfi, William Plumbly, T Grant Belgard, Emmanouil Metzakopian, Matthew G Hol. Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution. Molecular neurodegeneration. vol 19. issue 1. 2024-01-20. PMID:38245794. |
subpopulation analyses demonstrate a significant depletion of tyrosine hydroxylase (th) enriched astrocyte, microglia and oligodendrocyte populations in pd samples, as well as th enriched neurons, which are also depleted. |
2024-01-20 |
2024-01-23 |
human |
| Gabriela Goldberg, Luisa Coelho, Guoya Mo, Laura A Adang, Meenakshi Patne, Zhoutao Chen, Ivan Garcia-Bassets, Pinar Mesci, Alysson R Muotr. TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. Molecular psychiatry. 2023-12-22. PMID:38129659. |
functionally, trex1 in microglia is necessary for the transition from gliogenic intermediate progenitors known as pre-oligodendrocyte precursor cells (pre-opcs) to precursors of the oligodendrocyte lineage known as opcs, impairing oligodendrogenesis in favor of astrogliogenesis in human assembloids. |
2023-12-22 |
2023-12-24 |
human |
| Dan-Jie Wang, Xiao Wang, Shu-le Li, Tong-Tong Zhang, Ya-Chen Yang, Yu-Meng Wang, Xiao-Qiang Zhao, Kun-Yu Li, Yan-Qing Wang, Yan Li, Ke-Ying Zhu, Jun Wan. Sanguinarine modulates microglial function via PPARγ activation and protects against CNS demyelination. International immunopharmacology. vol 127. 2023-12-21. PMID:38128309. |
this creates a favorable milieu for the differentiation of oligodendrocyte progenitor cells (opcs) when opcs are incubated with conditioned medium from san-treated microglia. |
2023-12-21 |
2023-12-24 |
mouse |
| Tomoya Kon, Shelley L Forrest, Seojin Lee, Ivan Martinez-Valbuena, Jun Li, Nasna Nassir, Mohammed J Uddin, Anthony E Lang, Gabor G Kovac. Neuronal SNCA transcription during Lewy body formation. Acta neuropathologica communications. vol 11. issue 1. 2023-11-25. PMID:37996943. |
single-nucleus rna sequencing revealed that excitatory and inhibitory neurons, oligodendrocyte progenitor cells, oligodendrocytes, and homeostatic microglia expressed snca transcripts, while expression was largely absent in astrocytes and microglia. |
2023-11-25 |
2023-11-28 |
Not clear |
| A V S Sai Krishna, Alagammai Ramu, Srimathangi Hariharan, Swati Sinha, Sainitin Donakond. Characterization of tumor microenvironment in glioblastoma multiforme identifies ITGB2 as a key immune and stromal related regulator in glial cell types. Computers in biology and medicine. vol 165. 2023-09-03. PMID:37660569. |
we found following unique hub genes in immune infiltrated patients; col6a3 (microglia), itgam (oligodendrocyte precursor cells), tnfsf9 (microglia), and in stromal infiltrated patients, serpine1 (microglia) and thbs1 (newly formed oligodendrocytes, oligodendrocyte precursor cells). |
2023-09-03 |
2023-09-07 |
Not clear |
| Lara-Jasmin Schröder, Hauke Thiesler, Lina Gretenkort, Thiemo Malte Möllenkamp, Martin Stangel, Viktoria Gudi, Herbert Hildebrand. Polysialic acid promotes remyelination in cerebellar slice cultures by Siglec-E-dependent modulation of microglia polarization. Frontiers in cellular neuroscience. vol 17. 2023-07-26. PMID:37492129. |
polysia emerges as a negative regulator of inflammatory microglia and macrophage activation and has been detected on oligodendrocyte precursors and reactive astrocytes in multiple sclerosis lesions. |
2023-07-26 |
2023-08-14 |
Not clear |
| Xing Guo, Wenjun Hu, Zijie Gao, Yang Fan, Qianqian Wu, Weiguo L. Identification of PLOD3 and LRRN3 as potential biomarkers for Parkinson's disease based on integrative analysis. NPJ Parkinson's disease. vol 9. issue 1. 2023-05-31. PMID:37258507. |
the expression of plod3 was more enriched in inflammatory cell subpopulations, such as microglia, whereas lrrn3 was more enriched in neurons and oligodendrocyte progenitor cells clusters (opc). |
2023-05-31 |
2023-08-14 |
Not clear |
| Malosree Maitra, Haruka Mitsuhashi, Reza Rahimian, Anjali Chawla, Jennie Yang, Laura M Fiori, Maria Antonietta Davoli, Kelly Perlman, Zahia Aouabed, Deborah C Mash, Matthew Suderman, Naguib Mechawar, Gustavo Turecki, Corina Nag. Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes. Nature communications. vol 14. issue 1. 2023-05-22. PMID:37217515. |
among 7 broad cell types and 41 clusters evaluated, microglia and parvalbumin interneurons contributed the most degs in females, while deep layer excitatory neurons, astrocytes, and oligodendrocyte precursors were the major contributors in males. |
2023-05-22 |
2023-08-14 |
Not clear |
| Colin J Murray, Haley A Vecchiarelli, Marie-Ève Trembla. Enhancing axonal myelination in seniors: A review exploring the potential impact cannabis has on myelination in the aged brain. Frontiers in aging neuroscience. vol 15. 2023-04-10. PMID:37032821. |
furthermore, studies looking at the direct modulatory impact cannabis has on microglia, astrocytes and oligodendrocyte lineage cells hint at potential mechanisms to prevent some of the more damaging activities performed by these cells that contribute to demyelination in aging. |
2023-04-10 |
2023-08-14 |
Not clear |
| Yanzhuo Yang, Qingting Yu, Bin Li, Shijia Li, Zuisu Yang, Falei Yuan, Zhongliang Li. A single dose of lipopolysaccharide elicits autofluorescence in the mouse brain. Frontiers in aging neuroscience. vol 15. 2023-04-06. PMID:37020861. |
in the cortex, af occurs in the lysosomes of microglia, astrocytes, endothelial cells, and oligodendrocyte lineage cells and its prevalence increases with age. |
2023-04-06 |
2023-08-14 |
mouse |
| Monique M A de Almeida, Adrianne E S Watson, Sana Bibi, Nicole L Dittmann, Kara Goodkey, Pedram Sharafodinzadeh, Danny Galleguillos, Maryam Nakhaei-Nejad, Jayasankar Kosaraju, Noam Steinberg, Beatrix S Wang, Tim Footz, Fabrizio Giuliani, Jing Wang, Simonetta Sipione, Julia M Edgar, Anastassia Voronov. Fractalkine enhances oligodendrocyte regeneration and remyelination in a demyelination mouse model. Stem cell reports. 2023-01-07. PMID:36608690. |
finally, we show that activated opcs and microglia/macrophages express fractalkine receptor cx3cr1 in vivo, and that in opc-microglia co-cultures fractalkine increases in vitro oligodendrocyte differentiation by modulating both opc and microglia biology. |
2023-01-07 |
2023-08-14 |
mouse |
| Taylor C Clarkson, Nao Iguchi, Alison Xiaoqiao Xie, Anna P Malykhin. Differential transcriptomic changes in the central nervous system and urinary bladders of mice infected with a coronavirus. PloS one. vol 17. issue 12. 2022-12-09. PMID:36490282. |
transcriptome analysis of sc identified a significantly changed expression of >150 genes in cie mice known to regulate astrocyte, microglia and oligodendrocyte functions, neuroinflammation and immune responses. |
2022-12-09 |
2023-08-14 |
mouse |
| Pearl A Sutter, Stephen J Crocke. Glia as antigen-presenting cells in the central nervous system. Current opinion in neurobiology. vol 77. 2022-11-13. PMID:36371828. |
this review discusses these findings which incriminate microglia, astrocytes, and oligodendrocyte lineage cells as cns-resident apc types with implications for understanding disease. |
2022-11-13 |
2023-08-14 |
Not clear |
| Clayton A Wiley, Richard A Steinman, Qingde Wan. Innate immune activation without immune cell infiltration in brains of murine models of Aicardi-Gutiérrez Syndrome. Brain pathology (Zurich, Switzerland). 2022-09-26. PMID:36161399. |
within the cns aberrant isg expression was mostly limited to neurons, microglia, ependyma, choroid plexus, and endothelial cells with little expression in oligodendroglia and astrocytes except for stat1. |
2022-09-26 |
2023-08-14 |
mouse |
| Richard W Clayton, Robin Lovell-Badge, Christophe Galiche. The Properties and Functions of Glial Cell Types of the Hypothalamic Median Eminence. Frontiers in endocrinology. vol 13. 2022-08-15. PMID:35966104. |
the me contains many non-neuronal cell types, including oligodendrocytes, oligodendrocyte precursor cells (opcs), tanycytes, astrocytes, pericytes, microglia and other immune cells, which may be involved in the regulation of nes function. |
2022-08-15 |
2023-08-14 |
mouse |
| Yoshie Kawabe, Tatsuhide Tanaka, Ayami Isonishi, Kazuki Nakahara, Kouko Tatsumi, Akio Wanak. Characterization of Glial Populations in the Aging and Remyelinating Mouse Corpus Callosum. Neurochemical research. 2022-07-20. PMID:35859078. |
in the present study, with a multiplex staining method, semi-quantitative analysis of the localization of oligodendrocyte lineage cells (oligodendrocyte progenitors, premyelinating oligodendrocytes, and mature oligodendrocytes), astrocytes, and microglia in 8-week-old (young adult) and 32-week-old (aged) corpus callosum showed that young adult cells still include immature oligodendrocytes and that las contain a higher proportion of microglia than isolated cells. |
2022-07-20 |
2023-08-14 |
mouse |