| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zihao Li, Cun-Jin Zhan. Isolation and Culture of Mouse Primary Microglia and Oligodendrocyte Precursor Cells. Methods in molecular biology (Clifton, N.J.). vol 2782. 2024-04-15. PMID:38622401. |
microglia and oligodendrocyte precursor cells (opcs) are critical glia subsets in the central nervous system (cns) and are actively engaged in a body of diseases, such as stroke, alzheimer's disease, multiple sclerosis, etc. |
2024-04-15 |
2024-04-18 |
mouse |
| Weiwei Xian, Mohammad Asad, Shuai Wu, Zhixin Bai, Fengjiao Li, Junfeng Lu, Gaoyu Zu, Erin Brintnell, Hong Chen, Ying Mao, Guomin Zhou, Bo Liao, Jinsong Wu, Edwin Wang, Linya Yo. Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq analysis. Frontiers of medicine. 2023-11-13. PMID:37955814. |
by conducting single-cell rna-seq analyses on 26 gliomas, we reported their classification into primitive oligodendrocyte precursor cell (pri-opc)-like and radial glia (rg)-like tumors and validated it in a public cohort and tcga glioma. |
2023-11-13 |
2023-11-20 |
Not clear |
| Chih-Wei Zen. Macrophage-Neuroglia Interactions in Promoting Neuronal Regeneration in Zebrafish. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047456. |
furthermore, following spinal cord injury (sci), pmn progenitors have been observed to switch between oligodendrocyte and motor neuron fates, with macrophage-secreted tnf-α potentially regulating the differentiation of ependymal-radial glia progenitors and oligodendrocytes. |
2023-04-13 |
2023-08-14 |
human |
| Rasmani Hazra, Raditya Utama, Payal Naik, Alexander Dobin, David L Specto. Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA-sequencing datasets. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711961. |
we found three major gsc population clusters: radial glia, oligodendrocyte progenitor cells, and neurons. |
2023-01-30 |
2023-08-14 |
human |
| Feng-Yi Yang, Li-Hsin Huang, Meng-Ting Wu, Zih-Yun Pa. Ultrasound Neuromodulation Reduces Demyelination in a Rat Model of Multiple Sclerosis. International journal of molecular sciences. vol 23. issue 17. 2022-09-09. PMID:36077437. |
moreover, the ihc results showed that lipus significantly inhibited glial cell activation, enhanced mature oligodendrocyte density, and promoted brain-derived neurotrophic factor (bdnf) expression at the lesion site. |
2022-09-09 |
2023-08-14 |
rat |
| Rajeshwar Kumar Yadav, Sidharth Mehan, Rakesh Sahu, Sumit Kumar, Andleeb Khan, Hafiz Antar Makeen, Mohammed Al Bratt. Protective effects of apigenin on methylmercury-induced behavioral/neurochemical abnormalities and neurotoxicity in rats. Human & experimental toxicology. vol 41. 2022-04-04. PMID:35373622. |
mehg increases oligodendrocyte death, glial cell activation, and motor neuron demyelination in the motor cortex and spinal cord. |
2022-04-04 |
2023-08-13 |
rat |
| Dongeun Heo, Jonathan Ling, Gian C Molina-Castro, Abraham J Langseth, Ari Waisman, Klaus-Armin Nave, Wiebke Möbius, Phil C Wong, Dwight E Bergle. Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43. eLife. vol 11. 2022-03-21. PMID:35311646. |
although mislocalization and aggregation of the rna binding protein, tdp-43, occur in both neurons and glia in neurodegenerative diseases, the consequences of tdp-43 loss within different stages of the oligodendrocyte lineage are not well understood. |
2022-03-21 |
2023-08-13 |
Not clear |
| Hajime Takase, Gen Hamanaka, Ryo Ohtomo, Ji Hyun Park, Kelly K Chung, Irwin H Gelman, Kyu-Won Kim, Josephine Lok, Eng H Lo, Ken Ara. Roles of A-kinase Anchor Protein 12 in Astrocyte and Oligodendrocyte Precursor Cell in Postnatal Corpus Callosum. Stem cell reviews and reports. vol 17. issue 4. 2021-11-15. PMID:33492625. |
in addition, astrocytes expressed akap12 in the corpus callosum after birth, but oligodendrocyte precursor cells (opcs), another major type of glial cell in the developing corpus callosum, did not. |
2021-11-15 |
2023-08-13 |
mouse |
| Gregory J Heller, Michael S Marshall, Yazan Issa, Jeffrey N Marshall, Duc Nguyen, Emily Rue, Koralege C Pathmasiri, Miriam S Domowicz, Richard B van Breemen, Leon M Tai, Stephanie M Cologna, Stephen J Crocker, Maria I Givogri, Mark S Sands, Ernesto R Bongarzon. Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease. Molecular therapy : the journal of the American Society of Gene Therapy. vol 29. issue 5. 2021-11-11. PMID:33508430. |
our study shows that the dysregulation of therapeutic galc was likely driven by the exhaustion of therapeutic aav episomal dna within the lesions, paralleling the presence of proliferating oligodendrocyte progenitors and glia. |
2021-11-11 |
2023-08-13 |
mouse |
| Subhra Prakash Hui, Tapas Chandra Nag, Sukla Ghos. Neural cells and their progenitors in regenerating zebrafish spinal cord. The International journal of developmental biology. vol 64. issue 4-5-6. 2021-10-14. PMID:32658995. |
we have focused on event specific analyses of spinal cord regeneration involving different neuronal and glial cell progenitors, such as radial glia, oligodendrocyte progenitors (opc), and schwann cells. |
2021-10-14 |
2023-08-13 |
zebrafish |
| Elizabeth Minj, Shubham Upadhayay, Sidharth Meha. Nrf2/HO-1 Signaling Activator Acetyl-11-keto-beta Boswellic Acid (AKBA)-Mediated Neuroprotection in Methyl Mercury-Induced Experimental Model of ALS. Neurochemical research. vol 46. issue 11. 2021-10-04. PMID:34075522. |
mehg exposure also leads to oligodendrocyte destruction, glial cell overactivation, and demyelination of motor neurons in the motor cortex and spinal cord. |
2021-10-04 |
2023-08-13 |
rat |
| Jiangshan Zhan, Florian Nepomuk Fegg, Hannes Kaddatz, Sebastian Rühling, Julia Frenz, Bernd Denecke, Sandra Amor, Peter Ponsaerts, Tanja Hochstrasser, Markus Kip. Focal white matter lesions induce long-lasting axonal degeneration, neuroinflammation and behavioral deficits. Neurobiology of disease. vol 155. 2021-09-03. PMID:33932559. |
while myelination and oligodendrocyte densities appeared normal, ongoing axonal degeneration and glia cell activation were found in the remyelinated corpus callosum. |
2021-09-03 |
2023-08-13 |
mouse |
| Nabanita Mukherjee, Surajit Ghos. Myelin Associated Inhibitory Proteins as a Therapeutic Target for Healing of CNS Injury. ACS chemical neuroscience. vol 11. issue 12. 2021-06-18. PMID:32484646. |
apart from targeting the major inhibitory effect of glial scar associated proteoglycans like chondroitin sulfate and the reactive glial cell secreted inflammatory and growth inhibitory molecules, the other major regeneration stalling component that arises after severe cns injury is myelin and its associated proteinaceous debris comprising myelin-associated glycoprotein (mag), neurite outgrowth inhibitor protein (nogo), and oligodendrocyte myelin glycoprotein (omgp). |
2021-06-18 |
2023-08-13 |
Not clear |
| Misuzu Hashimoto, Ayako Kumabe, Jun-Dal Kim, Kazuya Murata, Sowmya Sekizar, Anna Williams, Weizhe Lu, Junji Ishida, Tsutomu Nakagawa, Mitsuharu Endo, Yasuhiro Minami, Akiyoshi Fukamiz. Loss of PRMT1 in the central nervous system (CNS) induces reactive astrocytes and microglia during postnatal brain development. Journal of neurochemistry. vol 156. issue 6. 2021-06-18. PMID:33460120. |
although we have previously discovered the crucial roles of prmt1 for oligodendrocyte lineage progression in the central nervous system of neural stem cell-specific prmt1 conditional knockout (prmt1-cko) mice, the context of other glial cell states that may cause the hypomyelination phenotype in prmt1-cko mice has not been explored so far. |
2021-06-18 |
2023-08-13 |
mouse |
| Aurélien Trimouille, Florent Marguet, Fanny Sauvestre, Eulalie Lasseaux, Fanny Pelluard, Marie-Laure Martin-Négrier, Claudio Plaisant, Caroline Rooryck, Didier Lacombe, Benoît Arveiler, Odile Boespflug-Tanguy, Sophie Naudion, Annie Laquerrièr. Foetal onset of EIF2B related disorder in two siblings: cerebellar hypoplasia with absent Bergmann glia and severe hypomyelination. Acta neuropathologica communications. vol 8. issue 1. 2021-05-31. PMID:32293553. |
bergmann glia was virtually absent associated to a drastic decreased number of mature astrocytes in the cerebellar white matter, multiple nestin-positive immature astrocytes as well as increased numbers of pdgrfα-positive oligodendrocyte precursors. |
2021-05-31 |
2023-08-13 |
Not clear |
| Sabah Mozafari, Laura Starost, Blandine Manot-Saillet, Beatriz Garcia-Diaz, Yu Kang T Xu, Delphine Roussel, Marion J F Levy, Linda Ottoboni, Kee-Pyo Kim, Hans R Schöler, Timothy E Kennedy, Jack P Antel, Gianvito Martino, Maria Cecilia Angulo, Tanja Kuhlmann, Anne Baron-Van Evercoore. Multiple sclerosis iPS-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivo. Science advances. vol 6. issue 49. 2021-03-17. PMID:33277253. |
multiple sclerosis ips-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivo. |
2021-03-17 |
2023-08-13 |
mouse |
| Seung Ro Han, Yun Hee Kang, Seung-Min Yoo, Myung-Shin Lee, Seung-Hoon Le. Diverse Gene Expressions in the Prediction of Cuprizone-Induced Demyelination. Neurotoxicity research. vol 37. issue 3. 2020-12-04. PMID:31916130. |
myelin abnormalities, oligodendrocyte damage, and concomitant glia activation are common characteristics of demyelinating diseases of the central nervous system. |
2020-12-04 |
2023-08-13 |
mouse |
| Seung Ro Han, Yun Hee Kang, Hyungtaek Jeon, Suhyuk Lee, Sang-Jin Park, Dae-Yong Song, Sun Seek Min, Seung-Min Yoo, Myung-Shin Lee, Seung-Hoon Le. Differential Expression of miRNAs and Behavioral Change in the Cuprizone-Induced Demyelination Mouse Model. International journal of molecular sciences. vol 21. issue 2. 2020-10-08. PMID:31963761. |
the demyelinating diseases of the central nervous system involve myelin abnormalities, oligodendrocyte damage, and consequent glia activation. |
2020-10-08 |
2023-08-13 |
mouse |
| Lisha Choubey, Jantzen C Collette, Karen Müller Smit. Quantitative assessment of fibroblast growth factor receptor 1 expression in neurons and glia. PeerJ. vol 5. 2020-10-01. PMID:28439461. |
for example, the fgfr1 receptor is important for proliferation and fate specification of radial glial cells in the cortex and hippocampus, oligodendrocyte proliferation and regeneration, midline glia morphology and soma translocation, bergmann glia morphology, and cerebellar morphogenesis. |
2020-10-01 |
2023-08-13 |
Not clear |
| David R Serwanski, Andrew L Rasmussen, Christopher B Brunquell, Scott S Perkins, Akiko Nishiyam. Sequential Contribution of Parenchymal and Neural Stem Cell-Derived Oligodendrocyte Precursor Cells toward Remyelination. Neuroglia (Basel, Switzerland). vol 1. issue 1. 2020-09-30. PMID:30662979. |
in the adult mammalian forebrain, oligodendrocyte precursor cells (opcs), also known as ng2 glia are distributed ubiquitously throughout the gray and white matter. |
2020-09-30 |
2023-08-13 |
Not clear |