| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joseph Kreis, Joseph Carrol. Applications of Adaptive Optics Imaging for Studying Conditions Affecting the Fovea. Annual review of vision science. 2024-04-18. PMID:38635871. |
the fovea is a highly specialized region of the central retina, defined by an absence of inner retinal layers and the accompanying vasculature, an increased density of cone photoreceptors, a near absence of rod photoreceptors, and unique private-line photoreceptor to midget ganglion cell circuitry. |
2024-04-18 |
2024-04-21 |
Not clear |
| Rumi Kawashima, Kenji Matsushita, Kenji Mandai, Yuko Sugita, Tomohiko Maruo, Kiyohito Mizutani, Yoshihiro Midoh, Akiko Oguchi, Yasuhiro Murakawa, Kazuki Kuniyoshi, Ryohei Sato, Takahisa Furukawa, Kohji Nishida, Yoshimi Taka. Necl-1/CADM3 regulates cone synapse formation in the mouse retina. iScience. vol 27. issue 4. 2024-04-16. PMID:38623325. |
necl-1/cadm3 regulates cone synapse formation in the mouse retina. |
2024-04-16 |
2024-04-18 |
mouse |
| Chris S Mesnard, Cassandra L Hays, Lou E Townsend, Cody L Barta, Channabasavaiah Gurumurthy, Wallace B Thoreso. SYNAPTOTAGMIN-9 IN MOUSE RETINA. bioRxiv : the preprint server for biology. 2024-03-19. PMID:37425946. |
our data show that syt9 is acts at multiple sites in the retina and suggest that it may play a role in regulating transmission of cone signals by rods. |
2024-03-19 |
2024-03-21 |
mouse |
| Maria Weller, Brigitte Müller, Knut Stiege. Long-Term Porcine Retina Explants as an Alternative to In Vivo Experimentation. Translational vision science & technology. vol 13. issue 3. 2024-03-13. PMID:38477924. |
the porcine retina represents an optimal model system to study treatment approaches for inherited retinal dystrophies owing to close anatomical similarities to the human retina, including a cone enriched visual streak. |
2024-03-13 |
2024-03-15 |
human |
| Malena Daich Varela, Mira Dixit, Angelos Kalitzeos, Michel Michaelide. Adaptive Optics Retinal Imaging in RDH12-Associated Early Onset Severe Retinal Dystrophy. Investigative ophthalmology & visual science. vol 65. issue 3. 2024-03-11. PMID:38466282. |
adaptive optics scanning light ophthalmoscopy (aoslo) enables resolution of individual rod and cone photoreceptors in the retina. |
2024-03-11 |
2024-03-14 |
Not clear |
| Emily R Sechrest, Robert J Barbera, Xiaojie Ma, Frank Dyka, Junyeop Ahn, Brooke A Brothers, Marion E Cahill, Isaac Hall, Wolfgang Baehr, Wen-Tao Den. Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function. Frontiers in neuroscience. vol 18. 2024-02-27. PMID:38410159. |
long-and middle-wavelength cone photoreceptors, which are responsible for our visual acuity and color vision, comprise ~95% of our total cone population and are concentrated in the fovea of our retina. |
2024-02-27 |
2024-03-02 |
mouse |
| Ceren Yalaz, Esther Bridges, Nasullah K Alham, Christos E Zois, Jianzhou Chen, Karim Bensaad, Ana Miar, Elisabete Pires, Ruth J Muschel, James S O McCullagh, Adrian L Harri. Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response. Cancer & metabolism. vol 12. issue 1. 2024-02-13. PMID:38350962. |
cone photoreceptor phosphodiesterase pde6h inhibition regulates cancer cell growth and metabolism, replicating the dark retina response. |
2024-02-13 |
2024-02-16 |
Not clear |
| Sarah E Hadyniak, Joanna F D Hagen, Kiara C Eldred, Boris Brenerman, Katarzyna A Hussey, Rajiv C McCoy, Michael E G Sauria, James A Kuchenbecker, Thomas Reh, Ian Glass, Maureen Neitz, Jay Neitz, James Taylor, Robert J Johnsto. Retinoic acid signaling regulates spatiotemporal specification of human green and red cones. PLoS biology. vol 22. issue 1. 2024-01-11. PMID:38206904. |
our data suggest that ra promotes m cone fate early in development to generate the pattern of m and l cones across the human retina. |
2024-01-11 |
2024-01-14 |
human |
| Gabrielle Lim-Kian-Siang, Arianna R Izawa-Ishiguro, Yong Ra. Neurexin-1-dependent circuit activity is required for the maintenance of photoreceptor subtype identity in Drosophila. Molecular brain. vol 17. issue 1. 2024-01-03. PMID:38167109. |
while recent studies have begun to reveal the mechanisms that specify the generation of cone subtypes during development in mammals, nothing is known about how the mosaic of mutually exclusive cone subtypes is maintained in the mammalian retina. |
2024-01-03 |
2024-01-06 |
human |
| Carlos Rodriguez, Ling-Qi Zhang, Alexandra E Boehm, Maxwell J Greene, William S Tuten, David H Brainar. Contributed Session II: Computational modeling of shift in unique yellow for small stimuli. Journal of vision. vol 23. issue 15. 2023-12-18. PMID:38109570. |
notably, reconstructions depend not only on the local l:m cone proportion, but also on the proportion in the immediately surrounding retina, leading to a testable prediction. |
2023-12-18 |
2023-12-21 |
Not clear |
| Mikayla L Puska, Michelle M Giarmarco, Jay Neitz, Maureen Neitz, James A Kuchenbecke. Poster Session II: Non-degenerating double cone opsin knockout mouse model of blue cone monochromacy. Journal of vision. vol 23. issue 15. 2023-12-18. PMID:38109588. |
despite the absence of both cone opsins, cones remain viable and morphologically normal, and the retina shows no signs of degeneration at 1 year. |
2023-12-18 |
2023-12-21 |
mouse |
| Mikayla L Puska, Michelle M Giarmarco, Jay Neitz, Maureen Neitz, James A Kuchenbecke. Poster Session II: Non-degenerating double cone opsin knockout mouse model of blue cone monochromacy. Journal of vision. vol 23. issue 15. 2023-12-18. PMID:38109588. |
this dko mouse model will be a valuable tool for developing gene therapies targeting cone opsins, and also for understanding color vision circuitry in the retina. |
2023-12-18 |
2023-12-21 |
mouse |
| Sierra Schleufer, Vimal Pandiyan, Bryna Hazelton, Daniel Coates, Ramkumar Sabesa. Poster Session II: Cone spacing and S-cone proportion is sufficient to describe varying S-cone regularity across the human central retina. Journal of vision. vol 23. issue 15. 2023-12-18. PMID:38109589. |
poster session ii: cone spacing and s-cone proportion is sufficient to describe varying s-cone regularity across the human central retina. |
2023-12-18 |
2023-12-21 |
human |
| Anna Vlasits, Maria M Korympidou, Sarah Strauss, Timm Schubert, Katrin Franke, Philipp Berens, Thomas Eule. Invited Session III: Diversity in chromatic processing across the animal kingdom: Color processing in the mouse retina. Journal of vision. vol 23. issue 15. 2023-12-18. PMID:38109634. |
in the mouse retina, cone photoreceptors possess a gradient of opsin expression leading to uneven detection of colors across visual space. |
2023-12-18 |
2023-12-21 |
mouse |
| Joo Yeun Lee, Luca Della Santina, Felice Dun. Invited Session II: Retinal remodeling and regeneration: Partial cone loss triggers differential modification of inhibition across retinal pathways. Journal of vision. vol 23. issue 15. 2023-12-18. PMID:38109641. |
to distinguish between these possibilities, our lab studied the effects of partial cone loss in the mature mouse retina. |
2023-12-18 |
2023-12-21 |
mouse |
| Joo Yeun Lee, Luca Della Santina, Felice Dun. Invited Session II: Retinal remodeling and regeneration: Partial cone loss triggers differential modification of inhibition across retinal pathways. Journal of vision. vol 23. issue 15. 2023-12-18. PMID:38109641. |
we examined the effects of 50% cone loss on the three of the most sensitive cell types in mouse retina: alpha on sustained (aon-s), off sustained (aoff-s), and off transient (aoff-t) ganglion cells. |
2023-12-18 |
2023-12-21 |
mouse |
| Daniel M Anderson, Danielle C Brager, Anthony J Kearsle. Spatially-dependent model for rods and cones in the retina. Journal of theoretical biology. 2023-12-16. PMID:38103677. |
rod and cone densities (number per unit area of retinal surface) are known to have significant spatial dependence in the retina with cones located primarily near the fovea and the rods located primarily away from the fovea. |
2023-12-16 |
2023-12-21 |
human |
| Sarah X Zhang, Josh J Wang, Christopher R Starr, Eun-Jin Lee, Sophia Park, Assylbek Zhylkibayev, Andy Medina, Jonathan H Lin, Marina Gorbatyu. The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease. Progress in retinal and eye research. 2023-12-13. PMID:38092262. |
in this review manuscript, we discuss the unique features of the er and er stress signaling in the retina and retinal neurons and describe recent advances in the research to uncover the role of er stress signaling in neurodegenerative retinal diseases including age-related macular degeneration, inherited retinal degeneration, achromatopsia and cone diseases, and diabetic retinopathy. |
2023-12-13 |
2023-12-17 |
human |
| Kaspar Gierke, Uwe Thorsten Lux, Hanna Regus-Leidig, Johann Helmut Brandstätte. The first synapse in vision in the aging mouse retina. Frontiers in cellular neuroscience. vol 17. 2023-12-01. PMID:38026697. |
in this study, we examined the first synapse of the visual system - the rod and cone photoreceptor ribbon synapse - in the mouse retina using light and electron microscopy at 2-3 months, ~1 year, and >2 years of age. |
2023-12-01 |
2023-12-10 |
mouse |
| Correction to: Sstr2 Defines the Cone Differentiation-Competent Late-Stage Retinal Progenitor Cells in the Developing Mouse Retina. Stem cells translational medicine. 2023-11-25. PMID:38006353. |
correction to: sstr2 defines the cone differentiation-competent late-stage retinal progenitor cells in the developing mouse retina. |
2023-11-25 |
2023-11-28 |
mouse |