| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paulo Cezar Rocha Dos Santos, Benedetta Heimler, Or Koren, Tamar Flash, Meir Plotni. Dopamine improves defective cortical and muscular connectivity during bilateral control of gait in Parkinson's disease. Communications biology. vol 7. issue 1. 2024-04-25. PMID:38658666. |
we thus conclude that dopamine corrects defective feedback caused by impaired sensory-information processing and sensory-motor integration, thus increasing cortico-muscular coherences in the alpha bands and improving gait. |
2024-04-25 |
2024-04-28 |
human |
| Koichi Tanaka, Mohammed E Choudhury, Satoshi Kikuchi, Ikuko Takeda, Kensuke Umakoshi, Noriyuki Miyaue, Kanta Mikami, Ayane Takenaga, Harumichi Yagi, Rintaro Shinabe, Hironori Matsumoto, Hajime Yano, Masahiro Nagai, Jun Takeba, Junya Tanak. A dopamine D1-like receptor-specific agonist improves the survival of septic mice. iScience. vol 27. issue 4. 2024-04-16. PMID:38623339. |
the expression of the proinflammatory cytokines tumor necrosis factor alpha (tnf-α) and interleukin-1β (il-1β) in the brain increased 6 h after clp but decreased 24 h later when elevated endogenous dopamine levels in the brain were sustained. |
2024-04-16 |
2024-04-18 |
mouse |
| Khaled G Abdel-Wahhab, Rehab S Sayed, Doaa G El-Sahra, Laila K Hassan, Ghada M Elqattan, Fathia A Manna. Echinacea purpurea extract intervention for counteracting neurochemical and behavioral changes induced by bifenthrin. Metabolic brain disease. 2023-12-27. PMID:38150137. |
also, bif induced a significant increase caspas-3, tumor necrosis factor alpha (tnf), and interleukin-1beta (il-1ß) in both areas; dopamine and serotonin levels, and ach-ase activity were markedly decreased in both areas. |
2023-12-27 |
2023-12-29 |
rat |
| Göksun Demirel, Sonia Sanajou, Anil Yirün, Deniz Arca Çakir, Aysel Berkkan, Terken Baydar, Pinar Erkekoğl. Evaluation of possible neuroprotective effects of virgin coconut oil on aluminum-induced neurotoxicity in an in vitro Alzheimer's disease model. Journal of applied toxicology : JAT. 2023-11-21. PMID:37989595. |
in addition, oxidative stress parameters (total antioxidant capacity, lipid peroxidase, protein carbonyl, and reactive oxygen species) and neurotransmitter-related parameters (dopamine, dopamine transporter acetylcholine, and synuclein alpha levels, acetylcholinesterase activity) were measured comparatively in the study groups. |
2023-11-21 |
2023-11-29 |
cattle |
| Wei Xu, Yuxin Song, Wenjun Xiao, Zhihua Gon. Regulatory Effects and Mechanisms of L-Theanine on Neurotransmitters via Liver-Brain Axis Under a High Protein Diet. Molecular neurobiology. 2023-09-02. PMID:37659037. |
we found that l-theanine regulates the activity of pf4 and g protein subunit alpha i2, increases the content of brain-derived neurotrophic factor and dopamine under a 20% protein diet. |
2023-09-02 |
2023-09-07 |
rat |
| Keisuke Suzuki, Tomohiro Tsuchiya, Koichi Hirat. [Pharmacological Treatment for Restless Legs Syndrome]. Brain and nerve = Shinkei kenkyu no shinpo. vol 75. issue 5. 2023-05-17. PMID:37194531. |
dopamine agonists and alpha 2-delta ligands are the first-line pharmacological treatments for rls. |
2023-05-17 |
2023-08-14 |
Not clear |
| Liping Zhou, Deqiang Han, Xingzhe Wang, Zhiguo Che. Probiotic Formulation VSL#3 Interacts with Mesenchymal Stromal Cells To Protect Dopaminergic Neurons via Centrally and Peripherally Suppressing NOD-Like Receptor Protein 3 Inflammasome-Mediated Inflammation in Parkinson's Disease Mice. Microbiology spectrum. 2023-02-02. PMID:36728426. |
hmscs, vsl#3 alone, and their combination markedly ameliorated the decreased striatal dopamine content, loss of dopaminergic neurons in the substantia nigra, increased levels of proinflammatory cytokines in serum, as well as tumor necrosis factor alpha (tnf-α) and interleukin-1β (il-1β) mrnas in striatum and peripheral tissues induced by mptp. |
2023-02-02 |
2023-08-14 |
mouse |
| Bidyut Dinda, Banibrata Das, Swati Biswas, Horrick Sharma, Christopher Armstrong, Deepthi Yedlapudi, Tamara Antonio, Maarten Reith, Aloke K Dutt. Bivalent dopamine agonists with co-operative binding and functional activities at dopamine D2 receptors, modulate aggregation and toxicity of alpha synuclein protein. Bioorganic & medicinal chemistry. vol 78. 2022-12-26. PMID:36571976. |
bivalent dopamine agonists with co-operative binding and functional activities at dopamine d2 receptors, modulate aggregation and toxicity of alpha synuclein protein. |
2022-12-26 |
2023-08-14 |
Not clear |
| Giulia Tomagra, Giulia Peroni, Pietro Aprà, Valentina Bonino, Matteo Campostrini, Valentina Carabelli, Cecilia Collà Ruvolo, Alessandro Lo Giudice, Laura Guidorzi, Lorenzo Mino, Paolo Olivero, Luca Pacher, Fabio Picariello, Alessandro Re, Valentino Rigato, Marco Truccato, Veronica Varzi, Ettore Vittone, Federico Picoll. Diamond-based sensors for in vitro cellular radiobiology: Simultaneous detection of cell exocytic activity and ionizing radiation. Biosensors & bioelectronics. vol 220. 2022-11-14. PMID:36375258. |
the devices were functionally characterized by testing both the above-mentioned detection schemes, namely: amperometric measurements of neurotransmitter release from excitable cells (such as dopamine or adrenaline) and dosimetric evaluation using different ionizing particles (alpha particle and x-ray photons). |
2022-11-14 |
2023-08-14 |
Not clear |
| Jameel N Hamdan, Jorge A Sierra-Fonseca, Rodolfo J Flores, Sigifredo Saucedo, Manuel Miranda-Arango, Laura E O'Dell, Kristin L Gosselin. Early-life adversity increases anxiety-like behavior and modifies synaptic protein expression in a region-specific manner. Frontiers in behavioral neuroscience. vol 16. 2022-11-07. PMID:36338879. |
the hippocampus (hipp), medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate putamen (cpu) were isolated from one subgroup of animals and subjected to western blot and protein quantitation for tyrosine hydroxylase (th), α-synuclein (alpha), nmda receptor (nmdar), dopamine receptor-1 (d1) and -2 (d2), dopamine transporter (dat), and postsynaptic density 95 (psd95). |
2022-11-07 |
2023-08-14 |
rat |
| Minghao Yan, Haibo Jin, Chun Pan, Hexing Hang, Dongmei Li, Xiaodong Ha. Movement Disorder and Neurotoxicity Induced by Chronic Exposure to Microcystin-LR in Mice. Molecular neurobiology. 2022-06-22. PMID:35732866. |
meanwhile, mc-lr induced the accumulation of alpha synuclein (α-syn) in da neurons and decreased the proteins of tyrosine hydroxylase (th), dopa decarboxylase (ddc) and dopamine transporter (dat), resulting in a reduction in dopamine (da) content, which are pathological features of parkinson's disease (pd). |
2022-06-22 |
2023-08-14 |
mouse |
| Khulekani Mncube, Marisa Möller, Brian H Harve. Post-weaning Social Isolated Flinders Sensitive Line Rats Display Bio-Behavioural Manifestations Resistant to Fluoxetine: A Model of Treatment-Resistant Depression. Frontiers in psychiatry. vol 12. 2021-12-07. PMID:34867504. |
post-mortem cortico-hippocampal norepinephrine (ne), serotonin (5-ht), and dopamine (da), as well as plasma interleukin 6 (il-6), tumour necrosis factor alpha (tnf-α), corticosterone (cort), and dopamine-beta-hydroxylase (dbh) levels were assayed. |
2021-12-07 |
2023-08-13 |
rat |
| Vera Kovaleva, Mart Saarm. Endoplasmic Reticulum Stress Regulators: New Drug Targets for Parkinson's Disease. Journal of Parkinson's disease. vol 11. issue s2. 2021-12-04. PMID:34180421. |
we have recently discovered that mesencephalic astrocyte-derived neurotrophic factor (manf) exerts its prosurvival action in dopamine neurons and in an animal model of pd through the direct binding to upr sensor inositol-requiring protein 1 alpha (ire1α) and attenuation of upr. |
2021-12-04 |
2023-08-13 |
Not clear |
| Qiong Wu, Maode Wang, Wei Chen, Kaili Wang, Yujing Wan. Daidzein exerts neuroprotective activity against MPTP-induced Parkinson's disease in experimental mice and lipopolysaccharide-induced BV2 microglial cells. Journal of biochemical and molecular toxicology. 2021-12-01. PMID:34850494. |
additionally, levels of dopamine were significantly reduced, and pro-inflammatory mediators tumor necrosis factor alpha (tnf-α), il-1β, il6 were found to be increased in mptp-induced c57bl6 pd mice. |
2021-12-01 |
2023-08-13 |
mouse |
| Angela M Thomas, Kaley J Cargile, Jannelle A Lunn, Lisa E Bake. Characterization of 3,4-methylenedioxypyrovalerone discrimination in female Sprague-Dawley rats. Behavioural pharmacology. vol 32. issue 6. 2021-11-05. PMID:34397448. |
stimulus substitution was assessed with mdpv and its enantiomers, other synthetic cathinones [alpha pyrrolidinopentiophenone-hydrochloride(α-pvp), 4-methylmethcathinone (4-mmc)], other dopamine agonists (cocaine, [+)-methamphetamine] and serotonin agonists [mdma, lysergic acid diethylamide (lsd)] stimulus antagonism was assessed with the dopamine d1 receptor antagonist, sch 23390 and the d2 receptor antagonist, haloperidol. |
2021-11-05 |
2023-08-13 |
rat |
| Oh-Chan Kwon, Jae-Jin Song, Yunseon Yang, Seong-Hoon Kim, Ji Young Kim, Min-Jong Seok, Inhwa Hwang, Je-Wook Yu, Jenisha Karmacharya, Han-Joo Maeng, Jiyoung Kim, Eek-Hoon Jho, Seung Yeon Ko, Hyeon Son, Mi-Yoon Chang, Sang-Hun Le. SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models. EMBO molecular medicine. vol 13. issue 4. 2021-10-25. PMID:33646633. |
along with those anti-inflammatory/neurotrophic functions, silencing and pharmacological inhibition of sgk1 protected midbrain dopamine neurons from degeneration and cured pathologic synuclein alpha (snca) aggregation and pd-associated behavioral deficits in multiple in vitro and in vivo pd models. |
2021-10-25 |
2023-08-13 |
Not clear |
| F Zanganeh, M Zendehdel, N Panahi, A Asghar. Interconnection between Adrenergic and Dopaminergic Systems in Feeding Behavior in Neonatal Chicks. Archives of Razi Institute. vol 76. issue 2. 2021-10-25. PMID:34223733. |
in the first experiment, chickens received the intracerebroventricular (icv) injection of a control solution, prazosin (i.e., α1 adrenergic receptor antagonist; 10 nmol), dopamine (da; 40 nmol), and prazosin plus da. |
2021-10-25 |
2023-08-13 |
Not clear |
| Yuksel Caki. Computational neuronal correlation with enhanced synchronized activity in the basal ganglia and the slowing of thalamic theta and alpha rhythms in Parkinson's disease. The European journal of neuroscience. vol 54. issue 3. 2021-08-23. PMID:34192822. |
the aim of this work is computationally to correlate the synchronized neuronal activity of basal ganglia and slowing in theta and alpha rhythms in electroencephalogram (eeg) signal in thalamic region in case of dopamine depletion and decrease of synaptic connections. |
2021-08-23 |
2023-08-13 |
Not clear |
| Andrew E Christie, J Joe Hull, Patsy S Dickinso. Assessment and comparison of putative amine receptor complement/diversity in the brain and eyestalk ganglia of the lobster, Homarus americanus. Invertebrate neuroscience : IN. vol 20. issue 2. 2021-07-09. PMID:32215729. |
all previously identified receptors were reidentified from the brain and/or eyestalk ganglia transcriptomes, i.e., dopamine alpha-1, beta-1, and alpha-2 (homam-daα2r) receptors, octopamine alpha (homam-octαr), beta-1, beta-2, beta-3, beta-4, and octopamine-tyramine (homam-otr-i) receptors, serotonin type-1a, type-1b (homam-5htr1b), type-2b, and type-7 receptors; and histamine type-1 (homam-ha1r), type-2, type-3, and type-4 receptors. |
2021-07-09 |
2023-08-13 |
lobster |
| Serenella Tolomeo, Benjamin Chiao, Zhen Lei, Soo Hong Chew, Richard P Ebstei. A Novel Role of CD38 and Oxytocin as Tandem Molecular Moderators of Human Social Behavior. Neuroscience and biobehavioral reviews. vol 115. 2021-06-21. PMID:32360414. |
acronyms: acc = anterior cingulate adp = adenosine diphosphate aq = autism quotient cadpr = cyclic adp-ribose cns = central nervous system da = dopamine eqtlc = expression quantitative trait loci lc-ne = locus coeruleus-norepinephrine mri = magnetic resonance imaging ofc = orbitofrontal cortices oxt = oxytocin rage = receptor for advanced glycation end-products sarm1 = sterile alpha and toll/interleukin-1 receptor motif-containing 1 trpm2= transient receptor potential cation channel subfamily m member 2 avp = vasopressin. |
2021-06-21 |
2023-08-13 |
human |