| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew P Gunn, Gregory M Rose, Alexis E Whitton, Diego A Pizzagalli, David G Gilber. Smoking Progression and Nicotine-Enhanced Reward Sensitivity Predicted by Resting-State Functional Connectivity in Salience and Executive Control Networks. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2024-04-16. PMID:38624067. |
we hypothesized that high rsfc between brain areas with high densities of nicotinic receptors (insula, anterior cingulate cortex [acc], hippocampus, thalamus) and areas involved in reward-seeking (nucleus accumbens [nacc], prefrontal cortex [pfc]) would predict nicotine-enhanced reward sensitivity and smoking progression. |
2024-04-16 |
2024-04-18 |
Not clear |
| David Petersen, Ricardo Raudales, Ariadna Kim Silva, Christoph Kellendonk, Sarah Canett. Adolescent Thalamocortical Inhibition Alters Prefrontal Excitation-Inhibition Balance. bioRxiv : the preprint server for biology. 2024-04-02. PMID:38562790. |
we found a decrease in the frequency of excitatory and inhibitory currents in layer ii/iii nucleus accumbens (nac) and layer v/vi medio-dorsal thalamus projecting neurons while layer v/vi nac-projecting neurons showed an increase in the amplitude of excitatory and inhibitory currents. |
2024-04-02 |
2024-04-04 |
mouse |
| Xiaoxi Zhao, Aqian Hu, Yanyan Wang, Tianshu Zhao, Xiaojun Xian. Paraventricular thalamus to nucleus accumbens circuit activation decreases long-term relapse of alcohol-seeking behaviour in male mice. Pharmacology, biochemistry, and behavior. 2024-02-15. PMID:38360104. |
the pathway from the anterior paraventricular thalamus (pvt) to the shell of the nucleus accumbens (nac) has been reported as an essential regulatory pathway for processing aversion and is also closely associated with substance addiction. |
2024-02-15 |
2024-02-18 |
mouse |
| Jacqueline E Paniccia, Kelsey M Vollmer, Lisa M Green, Roger I Grant, Kion T Winston, Sophie Buchmaier, Annaka M Westphal, Rachel E Clarke, Elizabeth M Doncheck, Bogdan Bordieanu, Logan M Manusky, Michael R Martino, Amy L Ward, Jennifer A Rinker, Jacqueline F McGinty, Michael D Scofield, James M Oti. Restoration of a paraventricular thalamo-accumbal behavioral suppression circuit prevents reinstatement of heroin seeking. Neuron. 2023-12-23. PMID:38141605. |
here, we employ deep-brain two-photon calcium imaging in heroin self-administering mice, longitudinally tracking adaptations within a paraventricular thalamus to nucleus accumbens behavioral inhibition circuit from the onset of heroin use to reinstatement. |
2023-12-23 |
2023-12-25 |
mouse |
| Acácio Moreira-Neto, Lucas Melo Neves, Angelo Miliatto, Valeria Juday, Raquel Marquesini, Beny Lafer, Ellison Fernando Cardoso, Carlos Ugrinowitsch, Mariana Penteado Nucci, Carla Silva-Batist. Clinical and neuroimaging correlates in a pilot randomized trial of aerobic exercise for major depression. Journal of affective disorders. vol 347. 2023-12-14. PMID:38092282. |
aerobic exercise (ae) combined with pharmacotherapy is known to reduce depressive symptoms; however, studies have not focused on long-term ae for volumetric changes of brain regions (amygdala, thalamus, and nucleus accumbens [nacc]) linked to the control of affective responses and hopelessness in individuals with major depression (md). |
2023-12-14 |
2023-12-17 |
Not clear |
| Su-Bin Hwang, Jae-Gyeong Lee, Youyoung Lee, Wun-A Kook, Seon-Kyung Kim, Audrey Lynn Donio, Hee-Won Min, Young-Jung Kim, Seok-Yong Lee, Choon-Gon Jan. Adinazolam, a Benzodiazepine-Type New Psychoactive Substance, Has Abuse Potential and Induces Withdrawal Symptoms in Rodents. ACS chemical neuroscience. 2023-09-11. PMID:37695876. |
after the ivsa test, an enzyme-linked immunosorbent assay (elisa) showed that adz administration significantly increased the dopamine contents in the thalamus, nucleus accumbens (nac), and ventral tegmental area (vta). |
2023-09-11 |
2023-10-07 |
mouse |
| Jean K Rivera-Irizarry, Peter U Hámor, Sydney A Rowson, Joseph Asfouri, Dezhi Liu, Lia J Zallar, Aaron F Garcia, Mary Jane Skelly, Kristen E Plei. Valence and salience encoding by parallel circuits from the paraventricular thalamus to the nucleus accumbens. bioRxiv : the preprint server for biology. 2023-07-18. PMID:37461604. |
the anterior and posterior subregions of the paraventricular thalamus (apvt and ppvt, respectively) play unique roles in learned behaviors, from fear conditioning to alcohol/drug intake, potentially through differentially organized projections to limbic brain regions including the nucleus accumbens medial shell (mnacsh). |
2023-07-18 |
2023-08-14 |
Not clear |
| Jimmy Olusakin, Gautam Kumar, Mahashweta Basu, Cali A Calarco, Megan E Fox, Jason B Alipio, Catherine Haga, Makeda D Turner, Asaf Keller, Seth A Ament, Mary Kay Lob. Transcriptomic profiling of reward and sensory brain areas in perinatal fentanyl exposed juvenile mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-03. PMID:37400565. |
rna was extracted from nucleus accumbens (nac), prelimbic cortex (prl), ventral tegmental area (vta), somatosensory cortex (s1) and ventrobasal thalamus (vbt) from perinatal fentanyl exposed mice of both sexes at p35. |
2023-07-03 |
2023-08-14 |
mouse |
| Maik Derksen, Birte Zuidinga, Marijke van der Veer, Valerie Rhemrev, Linda Jolink, Liesbeth Reneman, Aart Nederveen, Birte Forstmann, Matthijs Feenstra, Ingo Willuhn, Damiaan Deny. A comparison of how deep brain stimulation in two targets with anti-compulsive efficacy modulates brain activity using fMRI in awake rats. Psychiatry research. Neuroimaging. vol 330. 2023-02-16. PMID:36796237. |
bold-signal intensity was measured in five regions of interest (rois): medial and orbital prefrontal cortex, nucleus accumbens (nac), ic area, and mediodorsal thalamus. |
2023-02-16 |
2023-08-14 |
rat |
| Ryan P Bell, Sheri L Towe, Kareem Al-Khalil, Matthew Gibson, Tauseef Nadeem, Christina S Mead. Additive cortical gray matter deficits in people living with HIV who use cocaine. Journal of neurovirology. 2023-02-14. PMID:36787045. |
within subcortical regions, cocaine use was independently associated with higher volume in the dorsal striatum and pallidum, while hiv disease was associated with lower volume in the nucleus accumbens and thalamus. |
2023-02-14 |
2023-08-14 |
human |
| Zheng Gan, Vijayan Gangadharan, Sheng Liu, Christoph Körber, Linette Liqi Tan, Han Li, Manfred Josef Oswald, Juhyun Kang, Jesus Martin-Cortecero, Deepitha Männich, Alexander Groh, Thomas Kuner, Sebastian Wieland, Rohini Kune. Layer-specific pain relief pathways originating from primary motor cortex. Science (New York, N.Y.). vol 378. issue 6626. 2022-12-22. PMID:36548429. |
we unexpectedly unraveled a connection from the m1 to the nucleus accumbens reward circuitry through a m1 layer 6-mediodorsal thalamus pathway, which specifically suppresses negative emotional valence and associated coping behaviors in neuropathic pain. |
2022-12-22 |
2023-08-14 |
Not clear |
| Matthew G Engel, Jeremy Smith, Kai Mao, Gabriela Farias Quipildor, Min-Hui Cui, Maria Gulinello, Craig A Branch, Samuel E Gandy, Derek M Huffma. Evidence for preserved insulin responsiveness in the aging rat brain. GeroScience. 2022-07-07. PMID:35798912. |
despite these stark differences, icv insulin failed to elicit any significant alteration to the bold signal in young rats, while a significant deviation of the bold signal was observed in older animals, characterized by augmentation in regions of the septal nucleus and hypothalamus, and reduction in thalamus and nucleus accumbens. |
2022-07-07 |
2023-08-14 |
rat |
| Sophia C Levis, Matthew T Birnie, Jessica L Bolton, Christina R Perrone, Johanna S Montesinos, Tallie Z Baram, Stephen V Mahle. Enduring disruption of reward and stress circuit activities by early-life adversity in male rats. Translational psychiatry. vol 12. issue 1. 2022-06-15. PMID:35705547. |
we probe potential circuit mechanisms in males by assessing opioid-associated neuronal activation in stress and reward circuit nodes including nucleus accumbens (nac), amygdala, medial prefrontal cortex (mpfc), and paraventricular thalamus. |
2022-06-15 |
2023-08-14 |
rat |
| Sarah L Withey, Lei Cao, Fernando B de Moura, Kenroy R Cayetano, Michael L Rohan, Jack Bergman, Stephen J Kohu. Fentanyl-induced changes in brain activity in awake nonhuman primates at 9.4 Tesla. Brain imaging and behavior. 2022-02-28. PMID:35226333. |
subsequently, test sessions were conducted in which a dose of fentanyl that reliably maintains intravenous (iv) self-administration behavior in monkeys, 1 μg/kg, was administered and the effects on patterns of brain activity were assessed using: (1) a pharmacological regressor to elucidate fentanyl-induced patterns of neural activity, and (2) seed-based approaches targeting bilateral anterior cingulate, thalamus, or nucleus accumbens (nac) to determine alterations in cstc functional connectivity. |
2022-02-28 |
2023-08-13 |
monkey |
| Jing Liu, Lingxiao Cao, Hailong Li, Yingxue Gao, Xuan Bu, Kaili Liang, Weijie Bao, Suming Zhang, Hui Qiu, Xue Li, Xinyue Hu, Lu Lu, Lianqing Zhang, Xinyu Hu, Xiaoqi Huang, Qiyong Gon. Abnormal resting-state functional connectivity in patients with obsessive-compulsive disorder: A systematic review and meta-analysis. Neuroscience and biobehavioral reviews. 2022-02-13. PMID:35151769. |
quantitative coordinate-based meta-analysis was conducted for seed regions in the striatum (putamen, caudate, nucleus accumbens [nac]), thalamus, and anterior cingulate cortex (acc) because there were an adequate number of studies. |
2022-02-13 |
2023-08-13 |
Not clear |
| Yu Tang, Maohua Wang, Ting Zheng, Fengying Yuan, Han Yang, Fugang Han, Guangxiang Che. Grey matter volume alterations in trigeminal neuralgia: A systematic review and meta-analysis of voxel-based morphometry studies. Progress in neuro-psychopharmacology & biological psychiatry. vol 98. 2021-11-22. PMID:31756417. |
the results revealed that tn patients had gm volume abnormalities mainly in the basal ganglia, including the putamen, nucleus accumbens (nac), caudate nucleus and amygdala, as well as the cingulate cortex (cc), thalamus, insula and superior temporal gyrus (stg). |
2021-11-22 |
2023-08-13 |
Not clear |
| Rong-Jun Ni, Yu-Mian Shu, Tao Li, Jiang-Ning Zho. Whole-Brain Afferent Inputs to the Caudate Nucleus, Putamen, and Accumbens Nucleus in the Tree Shrew Striatum. Frontiers in neuroanatomy. vol 15. 2021-11-20. PMID:34795566. |
the cd and pu mainly received inputs from the thalamus, motor cortex, somatosensory cortex, subthalamic nucleus, substantia nigra, and other cortical and subcortical regions, whereas the acb primarily received inputs from the anterior olfactory nucleus, claustrum, infralimbic cortex, thalamus, raphe nucleus, parabrachial nucleus, ventral tegmental area, and so on. |
2021-11-20 |
2023-08-13 |
rat |
| Giuseppe Giannotti, Sheng Gong, Nicholas Fayette, Jasper A Heinsbroek, James E Orfila, Paco S Herson, Christopher P Ford, Jamie Peter. Extinction blunts paraventricular thalamic contributions to heroin relapse. Cell reports. vol 36. issue 8. 2021-09-07. PMID:34433067. |
here, we use optogenetics and chemogenetics to investigate the contribution of the paraventricular thalamus (pvt) to nucleus accumbens (nac) pathway in aversion and heroin relapse in two different heroin self-administration models in rats. |
2021-09-07 |
2023-08-13 |
rat |
| Dominik Thuberg, Lars Buentjen, Martin Holtkamp, Jürgen Voges, Hans-Jochen Heinze, Harim Lee, Ann-Yasmin Kitay, Friedhelm C Schmit. Deep Brain Stimulation for Refractory Focal Epilepsy: Unraveling the Insertional Effect up to Five Months Without Stimulation. Neuromodulation : journal of the International Neuromodulation Society. vol 24. issue 2. 2021-08-18. PMID:33577139. |
we examined the occurrence and duration of this ie in a group of patients with focal epilepsy following electrode implantation in the anterior nuclei of the thalamus (ant) and/or nucleus accumbens (nac) for dbs treatment. |
2021-08-18 |
2023-08-13 |
Not clear |
| Xingxing Zhu, Joey Ward, Breda Cullen, Donald M Lyall, Rona J Strawbridge, Laura M Lyall, Daniel J Smit. Phenotypic and genetic associations between anhedonia and brain structure in UK Biobank. Translational psychiatry. vol 11. issue 1. 2021-08-02. PMID:34282121. |
we found that state anhedonia was significantly associated with reduced total grey matter volume (gmv); increased total white matter volume (wmv); smaller volumes in thalamus and nucleus accumbens; reduced ct within the paracentral cortex, the opercular part of inferior frontal gyrus, precentral cortex, insula and rostral anterior cingulate cortex; and poorer integrity of many white matter tracts. |
2021-08-02 |
2023-08-13 |
human |